Target of Myb1 (Chicken)-Like 1 Proteins (TOM1L1)

Probable adapter protein involved in signaling pathways. Additionally we are shipping Target of Myb1 (Chicken)-Like 1 Antibodies (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TOM1L1 10040 O75674
TOM1L1 287622  
TOM1L1 71943  
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Top Target of Myb1 (Chicken)-Like 1 Proteins at

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

TOM1L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)

More Proteins for Target of Myb1 (Chicken)-Like 1 (TOM1L1) Interaction Partners

Human Target of Myb1 (Chicken)-Like 1 (TOM1L1) interaction partners

  1. TOM1L1 enhances ERBB2 (show ERBB2 Proteins)-induced cell invasiveness by promoting invadopodia formation and MT1-MMP (show MMP14 Proteins) trafficking to the plasma membrane.

  2. whereas TOM1L1 depletion only slightly affected SRC (show SRC Proteins)-induced proliferation of colorectal cancer cells in vitro, it drastically decreased tumor growth in xenografted nude mice.

  3. This pattern of Srcasm expression suggests that it may act as a negative regulator in esophageal squamous cell carcinoma cell signaling

  4. results imply that TOM1L has a mitogenic effect in Jurkat T-cells and is involved in a novel cell signaling pathway that is crucial for the IL-2 (show IL2 Proteins) production and STAT3 (show STAT3 Proteins) expression

  5. Srcasm plays a role in linking EGF receptor (show EGFR Proteins)- and SFK-dependent signaling to differentiation in keratinocytes

  6. Tom1L1 could act as an intermediary between signaling and degradative pathways.

  7. study found that not only the PTAP sequence in the GAT (show GLYAT Proteins) domain but also the PSAP (show PSAP Proteins) sequence in the C-terminal region of Tom1L1 is responsible for its interaction with the UEV domain of Tsg101 (show TSG101 Proteins) and competes with the HIV-1 Gag protein for the Tsg101 (show TSG101 Proteins) interaction

  8. All multicentric and nodular basal cell carcinomas displayed a prominent loss of Srcasm staining in association with a marked increase in Ki-67 (show MKI67 Proteins) staining.

  9. Participation of Tom1L1 in EGF (show EGF Proteins)-stimulated endocytosis of EGF receptor (show EGFR Proteins).

Mouse (Murine) Target of Myb1 (Chicken)-Like 1 (TOM1L1) interaction partners

  1. Tom1L1 defines a novel mechanism for regulation of Src (show SRC Proteins) family of protein-tyrosine kinases mitogenic signaling induced by growth factors.

  2. Srcasm may act as a molecular "rheostat" for activated Src (show SRC Proteins) family tyrosine kinases

  3. Tom1L1-clathrin heavy chain (CHC) complex negatively regulates the level of SFK in caveolae needed for the induction of DNA synthesis.

Target of Myb1 (Chicken)-Like 1 (TOM1L1) Protein Profile

Protein Summary

Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).

Gene names and symbols associated with TOM1L1

  • target of myb1-like 1 (tom1l1)
  • target of myb1 (chicken)-like 1 (TOM1L1)
  • target of myb1-like 1 (LOC100344255)
  • target of myb1 (chicken)-like 1 (Tom1l1)
  • target of myb1-like 1 (chicken) (Tom1l1)
  • 2310045L10Rik protein
  • C80573 protein
  • MGC52738 protein
  • OK/KNS-CL.3 protein
  • RGD1562626 protein
  • Srcasm protein
  • TOM1L1 protein

Protein level used designations for TOM1L1

target of myb1-like 1 , target of myb1 (chicken)-like 1 , TOM1-like protein 1 , TOM1-like protein 1-like , Src activating and signaling molecule , src-activating and signaling molecule protein , target of Myb-like protein 1 , target of myb 1-like 1 , Src-activating and signaling molecule protein , Target of Myb-like protein 1 , Jerry protein

379138 Xenopus laevis
417391 Gallus gallus
455138 Pan troglodytes
513303 Bos taurus
100170155 Xenopus (Silurana) tropicalis
100344255 Oryctolagus cuniculus
491093 Canis lupus familiaris
710262 Macaca mulatta
100399921 Callithrix jacchus
100446539 Pongo abelii
100467509 Ailuropoda melanoleuca
100522701 Sus scrofa
100595869 Nomascus leucogenys
10040 Homo sapiens
287622 Rattus norvegicus
71943 Mus musculus
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