Thrombospondin 2 Proteins (THBS2)

The protein encoded by THBS2 belongs to the thrombospondin family. Additionally we are shipping Thrombospondin 2 Antibodies (73) and Thrombospondin 2 Kits (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
THBS2 7058 P35442
THBS2 21826 Q03350
Rat THBS2 THBS2 292406  
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Top Thrombospondin 2 Proteins at

Showing 7 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 15 to 18 Days
HOST_Escherichia coli (E. coli) Mouse His tag   50 μg Log in to see 11 Days
Yeast Mouse His tag   50 μg Log in to see 8 to 11 Days
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days

THBS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine) , ,

More Proteins for Thrombospondin 2 (THBS2) Interaction Partners

Horse (Equine) Thrombospondin 2 (THBS2) interaction partners

  1. data suggest that THBS2 might modulate angiogenesis during wound healing in the horse, which could protect against the disproportionate fibroplasia commonly afflicting limb wounds and leading to the development of exuberant granulation tissue

Human Thrombospondin 2 (THBS2) interaction partners

  1. we report microRNA-135b (miR (show MLXIP Proteins)-135b), a key regulator of the malignancy, highly expressed in the RC component and promoting MLS cell invasion in vitro and metastasis in vivo through the direct suppression of thrombospondin 2 (THBS2).

  2. High THBS2 expression is associated with lung cancer.

  3. STMN1 (show STMN1 Proteins),COF1 (show CFL1 Proteins) and PAIRBP1 (show SERBP1 Proteins) thus represent proteins associated with proliferative and aggressive tumors of high grades, while TSP2 and POSTN (show POSTN Proteins) were connected to low grade tumors with better prognosis

  4. the tissue levels of THBS2 and LECT-2 (show LECT2 Proteins) may correlate with the stage of atherosclerosis.

  5. THBS2 and THBS4 (show THBS4 Proteins) mRNA are overexpressed in gastric cancer in a Southeast Chinese population.

  6. THBS2, but not COL1A2 (show COL1A2 Proteins) and SPP1 (show SPP1 Proteins), may serve as an indicator of gastric cancer prognosis.

  7. The level of THBS2 in differentiating stem cells, influences chondrogenic differentiation potential.

  8. THBS2 protein, human is predicting lymph node metastases in OSCC, overall survival and disease-free survival.

  9. Study suggests THBS2 is aberrantly expressed in gastric cancer and plays a critical role in cancer progression.

  10. No association was observed between the THBS2 3' untranslated region polymorphism and coronary artery disease risk.

Cow (Bovine) Thrombospondin 2 (THBS2) interaction partners

  1. Data suggest THBS1 (show THBS1 Proteins) expression predominates in luteal endothelial cells; THBS2 expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1 (show THBS1 Proteins)/THBS2, up-regulates expression of FGF2 (fibroblast growth factor 2 (show FGF2 Proteins)).

  2. TSP-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.

Mouse (Murine) Thrombospondin 2 (THBS2) interaction partners

  1. TSP2 deficiency imparted a brittle phenotype on cortical bone. electron microscopy revealed less intensely stained collagen fibrils with altered morphology in the extracellular matrix assembled by osteoblasts on the anterior surface of TSP2-KO femora.

  2. Enhanced levels of TSP-2 in the skin result in reduced susceptibility to chemically-induced skin carcinogenesis.

  3. in the context of osteoblast differentiation, TSP2 promotes the assembly of a type-I collagen-rich matrix by facilitating pro-collagen processing.

  4. The proposed mechanism for the shift in stem cell fate in fracture healing is that increased vascular density and hence oxygen availability in TSP2-null mice regulates differentiation.

  5. The upregulation of TSP-2 mediated by increased oxidative stress contributes to angiogenesis dysfunction in diabetic bone marrow derived angiogenic cells.

  6. TSP2 is a negative regulator of ischemic fracture healing, and in the absence of TSP2 bone regeneration is enhanced.

  7. Using a TSP-2-knockout mouse model and cardiac cell transplantation, we found significantly reduced fibrosis and increased endothelial cell density in the peri (show POSTN Proteins)-graft region.

  8. TSP1 (show GZMA Proteins)-null and TSP2-null mice have lower IOPs than their WT counterparts. The rate of aqueous turnover suggests that the mechanism is enhanced outflow facility.

  9. the two TSP2 isforms are differentially modulated at injured and noninjured skeletal sites in an animal undergoing fracture healing.

  10. TSP-2 has a protective role against cardiac inflammation, injury, and dysfunction in acute viral myocarditis.

Thrombospondin 2 (THBS2) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.

Gene names and symbols associated with Thrombospondin 2 Proteins (THBS2)

  • thrombospondin 2 (THBS2)
  • thrombospondin 2 (thbs2)
  • thrombospondin 2a (thbs2a)
  • thrombospondin 2 (LOC100221289)
  • thrombospondin 2 (Thbs2)
  • thrombospondin 2 (LOC100357972)
  • thrombospondin-2-like (LOC100153940)
  • Thbs-2 protein
  • THBS1 protein
  • thbs2 protein
  • TMEM200A protein
  • TSP-2 protein
  • TSP2 protein

Protein level used designations for Thrombospondin 2 Proteins (THBS2)

thrombospondin-2 , thrombospondin 2 , Tsp-2 , CISP , corticotropin-induced secreted protein , transmembrane protein 200A

484087 Canis lupus familiaris
100050044 Equus caballus
708165 Macaca mulatta
779026 Xenopus laevis
794881 Danio rerio
100221289 Taeniopygia guttata
7058 Homo sapiens
338092 Bos taurus
21826 Mus musculus
414837 Gallus gallus
292406 Rattus norvegicus
100357972 Oryctolagus cuniculus
100735538 Cavia porcellus
100153940 Sus scrofa
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