anti-Tocopherol (Alpha) Transfer Protein (TTPA) Antibodies

TTPA encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. Additionally we are shipping TTPA Kits (11) and TTPA Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TTPA 7274 P49638
TTPA 25571 P41034
TTPA 50500 Q8BWP5
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Top anti-TTPA Antibodies at

Showing 10 out of 29 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB TTPA Antibody (Center) (ABIN1881957) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the TTPA antibody detected the TTPA protein (arrow). 400 μL Log in to see 10 to 11 Days
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using TTPA antibody. 100 μL Log in to see 16 Days
Hamster Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry: Alpha-TTP Antibody [NBP2-14870] - Paraffin-embedded gastric carcinoma; antibody dilution 1:500. Western Blot: Alpha-TTP Antibody [NBP2-14870] - Sample (30 ug of whole cell lysate) A: IMR32 12% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
Mouse Rabbit Un-conjugated ICC, IHC, IP, WB   100 μg Log in to see 13 to 16 Days
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL Log in to see 11 to 12 Days
Human Mouse Un-conjugated ELISA, WB   50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB Western blot analysis in CEM cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days

TTPA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)

Mouse (Murine)

Top referenced anti-TTPA Antibodies

  1. Human Polyclonal TTPA Primary Antibody for WB - ABIN1881957 : Wirth, Poletti, Aeschlimann, Yakandawala, Drosse, Osorio, Tohge, Fernie, Günther, Gruissem, Sautter: Rice endosperm iron biofortification by targeted and synergistic action of nicotianamine synthase and ferritin. in Plant biotechnology journal 2009 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal TTPA Primary Antibody for ELISA, WB - ABIN1327290 : Qu, Fu, Liu, Zuo, Jia, Ma, Luo: Screening of α-Tocopherol Transfer Protein Sensitive Genes in Human Hepatoma Cells (HepG2). in International journal of molecular sciences 2016 (PubMed)

More Antibodies against TTPA Interaction Partners

Human Tocopherol (Alpha) Transfer Protein (TTPA) interaction partners

  1. These findings provide the basis for a proposed mechanistic model that describes TTP (show ADAMTS13 Antibodies)-facilitated trafficking of alpha-tocopherol through hepatocytes.

  2. Single-nucleotide polymorphisms that are commonly found in healthy humans dramatically affect promoter activity of the TTPA gene.

  3. The crystal structure of the alpha-TTP-phosphatidylinositol phosphates (PIPs (show GPRASP1 Antibodies)) complex revealed that the familial vitamin E deficiency-related arginine residues interacted with phosphate groups of the PIPs (show GPRASP1 Antibodies) and that the PIPs (show GPRASP1 Antibodies) binding caused the lid of the alpha-tocopherol-binding pocket to open.

  4. Data show that reduction ("knockdown") of tocopherol transfer protein (TTP (show ADAMTS13 Antibodies)) expression resulted in resistance to the vitamin E.

  5. Substitution of residues in helices A8 (F165A and F169A) and A10 (I202A, V206A and M209A) decreased the rate of intermembrane ligand transfer as well as protein adsorption to phospholipid bilayers.

  6. First case of a mutated form of the TTPA gene in a patient also carrying a spinocerebellar ataxia type 8 expansion.

  7. the positively charged surface of TTPA may serve to orient an interacting protein, which might function to regulate the release of alpha-T through an induced change in conformation of ATTP

  8. Findings suggest the possibility that ataxia with vitamin E deficiency syndrome (AVED) may not arise from an inability of TTP (show ADAMTS13 Antibodies) to bind or to transfer alpha tocopherol, but rather from defects in other activities of the protein.

  9. Nuclear localization of TTPA in in trophoblast, fetal capillaries' endothelium and amnion epithelium of human term placentamay represent a novel function of TTPA

  10. In Ataxia with vitamin E deficiency two TTPA mutations were identified: a truncating mutation in a homozygous patient, and a Gly246Arg missense mutation in a compound heterozygous patient associated with a mild and slowly progressive form of the disease.

Mouse (Murine) Tocopherol (Alpha) Transfer Protein (TTPA) interaction partners

  1. Results suggest that lipid peroxidation due to depletion of alpha-tocopherol impairs Abeta (show APP Antibodies) clearances from the brain and from the blood, possibly causing increased Abeta (show APP Antibodies) accumulation in Ttpa(-/-)APPsw brain and plasma.

  2. Endogenous TTPA, through the enhancement of MMP 9 (show MMP9 Antibodies) expression and proteolytic activation, plays an essential role in the pathogenesis of heparin-produced cerebral hemorrhage.

  3. TTP (show ZFP36 Antibodies) transports alpha-TCP and oral administration of TTP (show ZFP36 Antibodies) compensates for TTP (show ZFP36 Antibodies) in TTP (show ZFP36 Antibodies)-deficient mice

  4. These data suggest that in vivo network of alpha-tocopherol (AT), AT-metabolites and ATTP (show UEVLD Antibodies) affects the transcription of genes driven by AhR (show AHR Antibodies), Nrf2 (show NFE2L2 Antibodies) and NF-kappaB (show NFKB1 Antibodies), transcription factor networks.

  5. p75(NTR (show NGFR Antibodies))is up-regulated after tissue injury, blocks fibrinolysis by down-regulating the serine protease (show F2 Antibodies), tissue plasminogen activator (show PLAT Antibodies), and up-regulating PAI-1 (show SERPINE1 Antibodies).

  6. changes in hepatic TTP (show ZFP36 Antibodies) concentrations were minimal in response to dietary vitamin E levels or environmental tobacco smoke-related oxidative stress

  7. Increase expression of tPA implicate fibrinolysis in ALD progression.

TTPA Antigen Profile

Protein Summary

This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.

Gene names and symbols associated with TTPA

  • tocopherol (alpha) transfer protein (TTPA) antibody
  • tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) (ttpa) antibody
  • tocopherol (alpha) transfer protein (Ttpa) antibody
  • alpha-TTP antibody
  • alphaTTP antibody
  • ATTP antibody
  • AVED antibody
  • TTP antibody
  • TTP1 antibody

Protein level used designations for TTPA

alpha-tocopherol transfer protein , tocopherol (alpha) transfer protein , alpha-TTP , tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) , Alpha-tocopherol transfer protein , Tocopherol transfer protein alpha , alpha TTP

286813 Bos taurus
403627 Canis lupus familiaris
472778 Pan troglodytes
771074 Gallus gallus
100196332 Salmo salar
100526668 Ovis aries
7274 Homo sapiens
25571 Rattus norvegicus
50500 Mus musculus
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