anti-Transmembrane Protein 43 (TMEM43) Antibodies

TMEM43 belongs to the TMEM43 family. Additionally we are shipping TMEM43 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMEM43 79188 Q9BTV4
TMEM43 74122 Q9DBS1
Anti-Rat TMEM43 TMEM43 362401 Q5XIP9
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Top anti-TMEM43 Antibodies at

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB TMEM43 Antibody (Center)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TMEM43 antibody detected the TMEM43 protein (arrow). TMEM43 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TMEM43 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using TMEM43 antibody. Immunohistochemistry of paraffin-embedded human gastric using TMEM43 antibody at dilution of 1:100 (x40 lens). 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 10 to 13 Days
Human Rabbit Un-conjugated IHC (p), WB   400 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, IHC, WB   200 μL Log in to see 7 to 9 Days
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days

TMEM43 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,

, , , , ,
Mouse (Murine)

Top referenced anti-TMEM43 Antibodies

  1. Human Polyclonal TMEM43 Primary Antibody for ICC, IF - ABIN4360711 : Christensen, Andersen, Tybjaerg-Hansen, Haunso, Svendsen: Mutation analysis and evaluation of the cardiac localization of TMEM43 in arrhythmogenic right ventricular cardiomyopathy. in Clinical genetics 2011 (PubMed)

More Antibodies against TMEM43 Interaction Partners

Human Transmembrane Protein 43 (TMEM43) interaction partners

  1. A very rare mutation in TMEM 43 for the development of Arrhythmogenic cardiomyopathy has a definite connection with desmosomal proteins (plakoglobin (show JUP Antibodies)) and justifies in a highly arrhythmogenic form of the disease.

  2. Implantable cardioverter defibrillator therapy is indicated for primary prevention in postpubertal males and in females >/= 30 years with the p.S358L TMEM43 mutation.

  3. These observations suggest that expression of the p.S358L mutant of TMEM43 found in ARVC type 5 may affect localization of proteins involved in conduction, alter gap junction function and reduce conduction velocity in cardiac tissue.

  4. ARVC due to p.S358L in TMEM43 is a variant form of ARVC with extreme variability of expression. It is sex influenced: males are more frequently hospitalized and have heart failure and SCD (show SCD Antibodies) at a younger age than females.

  5. TMEM43 mutations occur outside of the founder population of the island of Newfoundland where it was originally described.

  6. full gene sequencing of TMEM43 in 143 ARVC probands (families) from the UK revealed three potential pathogenic variants (p.R312W, p.R28W, p.E142K). The p.R312W missense variant is a recurrent mutation due to a founder effect and is likely pathogenic.

  7. Ser358Leu mutant TMEM43 exhibits normal cellular localization and does not disrupt integrity and localization of other nuclear envelope and desmosomal proteins.

  8. The TMEM43 gene underlies a distinctive form of arrhythmogenic right ventricular cardiomyopathy (ARVC) which may share a final common pathway with desmosome-associated ARVC.

  9. The results of study suggested that mutant LUMAs may be associated with EDMD (show EMD Antibodies)-related myopathy.

  10. Studies indicate that in 2007, the Newfoundland local research team discovered the causative mutation in a novel gene TMEM43 within the disease-associated founder haplotype.

TMEM43 Antigen Profile

Protein Summary

This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Gene names and symbols associated with TMEM43

  • transmembrane protein 43 (TMEM43) antibody
  • transmembrane protein 43 (tmem43) antibody
  • Transmembrane protein 43 (tmm43) antibody
  • transmembrane protein 43 (Tmem43) antibody
  • 1200015A22Rik antibody
  • ARVC5 antibody
  • ARVD5 antibody
  • EDMD7 antibody
  • LUMA antibody
  • zgc:85946 antibody

Protein level used designations for TMEM43

elastin , transmembrane protein 43 , Transmembrane protein 43

404066 Bos taurus
406520 Danio rerio
416038 Gallus gallus
460194 Pan troglodytes
484637 Canis lupus familiaris
700689 Macaca mulatta
100170516 Xenopus (Silurana) tropicalis
100346020 Oryctolagus cuniculus
100380459 Salmo salar
100474642 Ailuropoda melanoleuca
100588388 Nomascus leucogenys
79188 Homo sapiens
74122 Mus musculus
362401 Rattus norvegicus
100172804 Pongo abelii
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