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anti-Trefoil Factor 3 (Intestinal) (TFF3) Antibodies

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Additionally we are shipping TFF3 Kits (75) and TFF3 Proteins (49) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TFF3 7033 Q07654
TFF3 21786 Q62395
TFF3 25563 Q03191
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Top anti-TFF3 Antibodies at

Showing 10 out of 144 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TFF3 in rat small intestine tissue lysate with TFF3 antibody at 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded: mouse small intestine tissue labeled with Anti-TFF3 Polyclonal Antibody (ABIN669786), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining HT-29 cells probed with Rabbit Anti-TFF3 Polyclonal Antibody  Alexa Fluor 488 Conjugated Secondary Antibody. 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated IHC, ELISA, WB The TFF3 Antibody is used in Western blot to detect TFF3 in rat stomach lysate. TFF3 staining in human gastric tissue. Paraffin-embedded human gastric tissue is stained with TFF3 Antibody used at 1:200 dilution 0.1 mg Log in to see 2 to 6 Days
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TFF3 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged TFF3 is approximately 0.03ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TFF3 is approximately 0.1ng/ml as a capture antibody. Western Blot detection against Immunogen (32.23 KDa) . 50 μg Log in to see 11 to 12 Days
Human Rabbit PE FACS   100 μL Log in to see 3 to 7 Days
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
Human Mouse Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
Mouse Rabbit Un-conjugated ELISA, IHC (p), WB   100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days

TFF3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TFF3 Antibodies

  1. Human Monoclonal TFF3 Primary Antibody for IHC (p), ELISA - ABIN563166 : Bignotti, Ravaggi, Tassi, Calza, Rossi, Falchetti, Romani, Bandiera, Odicino, Pecorelli, Santin: Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas. in British journal of cancer 2008 (PubMed)
    Show all 7 references for ABIN563166

  2. Human Polyclonal TFF3 Primary Antibody for EIA, WB - ABIN783349 : Zhao, Li, Pan, Liu, Lv, Leung, Lu: Enhanced gene delivery by chitosan-disulfide-conjugated LMW-PEI for facilitating osteogenic differentiation. in Acta biomaterialia 2013 (PubMed)

  3. Human Polyclonal TFF3 Primary Antibody for FACS - ABIN2179568 : Kimura, van der Merwe, Bering, Penmatsa, Conoley, Sangild, Naren, Buddington: Glucose transport by epithelia prepared from harvested enterocytes. in Cytotechnology 2015 (PubMed)

  4. Human Monoclonal TFF3 Primary Antibody for ELISA, WB - ABIN563167 : Hamady, Farrar, Whitehead, Holland, Lodge, Carding: Identification and use of the putative Bacteroides ovatus xylanase promoter for the inducible production of recombinant human proteins. in Microbiology (Reading, England) 2008 (PubMed)

  5. Human Polyclonal TFF3 Primary Antibody for IHC, ELISA - ABIN1585377 : Borniquel, Jädert, Lundberg: Dietary conjugated linoleic acid activates PPARγ and the intestinal trefoil factor in SW480 cells and mice with dextran sulfate sodium-induced colitis. in The Journal of nutrition 2012 (PubMed)

More Antibodies against TFF3 Interaction Partners

Human Trefoil Factor 3 (Intestinal) (TFF3) interaction partners

  1. TFF3 levels differed among idiopathic pulmonary fibrosis, pulmonary sarcoidosis and chronic pulmonary obstructive disease.

  2. TFF3 protein knockout can facilitate apoptosis of human pituitary adenoma HP75 cells via mitochondrial pathway

  3. Data show that trefoil factor-3 (TFF3) secreted from mammary carcinoma cells promotes de novo angiogenesis via interleukin-8 (IL-8 (show IL8 Antibodies))/IL-8 (show IL8 Antibodies) receptor (show CXCR1 Antibodies) CXCR2 (show CXCR2 Antibodies).

  4. Dimers CXCR4 (show CXCR4 Antibodies) and CXCR7 (show CXCR7 Antibodies) are involved in TFF3-dependent activation of cell migration, but not cell proliferation. The ERK1/2 (show MAPK1/3 Antibodies) pathway is activated in the process, but not influenced by CXCR4 (show CXCR4 Antibodies) or CXCR7 (show CXCR7 Antibodies).

  5. These findings suggest that the rs184432 and rs225359 polymorphisms in TFF1 (show TFF1 Antibodies) have protective effects for GC and contribute to the development of GC in Korean individuals.

  6. TFF3 expression is associated with response to endocrine therapy, and outperforms oestrogen receptor, progesterone receptor (show PGR Antibodies) and TFF1 (show TFF1 Antibodies) as an independent biomarker, possibly because it mediates the malign effects of oestrogen on invasion and metastasis

  7. the results provide a mechanistic explanation for ITF-mediated protection of gastric epithelial mucosa cells, suggesting that activation of the ERK1/2 (show MAPK1/3 Antibodies) signaling pathway may provide a new therapeutic strategy for repairing gastric injury.

  8. primary outcome measures were to evaluate the safety, acceptability, and accuracy of the Cytosponge-TFF3 test compared with endoscopy and biopsy. In all, 1,042 (93.9%) patients successfully swallowed the Cytosponge, and there were no serious side effects

  9. TFF3 is not only a useful biomarker for a long-term surgical result in CRC (show CALR Antibodies) patient, but also may be a risk factor of early recurrence.

  10. Associations discovered between trefoil factor 3 gene variants and idiopathic recurrent spontaneous abortion.

Mouse (Murine) Trefoil Factor 3 (Intestinal) (TFF3) interaction partners

  1. the Tg(Tff1 (show TFF1 Antibodies)-CreERT2;Tff2 (show TFF2 Antibodies)-rtTA;Tff3-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous gene modification, and may be suitable to genetically model therapeutic intervention during development, tumorigenesis, and other genetically tractable diseases

  2. TFF3 is regulated by food intake, improves glucose tolerance and induces mucinous metaplasia.

  3. TFF1 (show TFF1 Antibodies) and TFF3 peptides might be involved in the complex processes of nervous system development and differentiation and brain plasticity.

  4. The TFF3 was present in cartilage chondrocytes undergoing endochondral ossification, particularly in zone of proliferation, hypertrophy and calcification as well as in zone of cartilage degeneration during the monitored fetal period.

  5. Intravenous administration of recombinant TFF3 reversed changes in cerebral injury.

  6. Tff3 peptides are involved in glucose homeostasis and insulin (show INS Antibodies) sensitivity, providing a promising peptide on new therapies against the metabolic disorders associated with type 2 diabetes mellitus.

  7. The genetically deleting Tff3 in mice altered down-regulated Pttg1 and up-regulated serpina3n expression, indicating a potential role of these factors during the development of presbyacusis.

  8. Tff3 knock out mice have lower body weight than wild-type mice.

  9. Soy protein diet, but not Lactobacillus rhamnosus GG, decreases mucin-1 (show MUC1 Antibodies), trefoil factor-3, and tumor necrosis factor-alpha (show TNF Antibodies) in colon of dextran sodium sulfate-induced colitis.

  10. results suggest that a diminution of the intestinal trefoil factor system may be involved in the acceleration of aging in SAM (show TTN Antibodies)-P6 mice

TFF3 Antigen Profile

Protein Summary

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Gene names and symbols associated with TFF3

  • trefoil factor 3 (intestinal) (TFF3) antibody
  • trefoil factor 3 (intestinal) (Tff3) antibody
  • trefoil factor 3-like (LOC100739705) antibody
  • trefoil factor 3, intestinal (Tff3) antibody
  • ITF antibody
  • mITF antibody
  • P1B antibody
  • TFF3 antibody
  • TFI antibody

Protein level used designations for TFF3

trefoil factor 3 (intestinal) , polypeptide P1.B , trefoil factor 3 , intestinal trefoil factor , Intestinal trefoil factor , trefoil factor family peptide 3

474124 Pan troglodytes
7033 Homo sapiens
100732911 Cavia porcellus
517889 Bos taurus
100627480 Sus scrofa
100170655 Felis catus
403488 Canis lupus familiaris
780497 Ovis aries
100739705 Sus scrofa
21786 Mus musculus
25563 Rattus norvegicus
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