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Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Additionally we are shipping TNNI1 Antibodies (56) and TNNI1 Proteins (7) and many more products for this protein.
Showing 8 out of 23 products:
Rat (Rattus) TNNI1 ELISA Kit for Sandwich ELISA - ABIN433505
Lichtenauer, Mildner, Hoetzenecker, Zimmermann, Podesser, Sipos, Berényi, Dworschak, Tschachler, Gyöngyösi, Ankersmit: Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study. in Basic research in cardiology 2011
CT-1 (show CTF1 ELISA Kits) was found to be associated with Tn-I, which is used to detect myocardial damage after OPCAB surgery. CT-1 (show CTF1 ELISA Kits) may also be used to detect myocardial damage.
TNNI3K (show TNNI3K ELISA Kits) is a cardiac-specific gene, encoding a cardiac troponin I (show TNNI3 ELISA Kits)-interacting MAP kinase (show MAPK1 ELISA Kits). In mice, Tnni3k (show TNNI3K ELISA Kits) is shown to play an important role in the regulation of cardiac differentiation and cardiac contractility
Data suggest that mutation A162H in switch region of troponin I induces transitory curved conformation and promotes contraction of troponin I bound to regulatory domain of troponin C; this is countered by residue E164 to ensure proper relaxation.
Elevations of troponin I and N-terminal pro-B-type natriuretic peptide (show BNP ELISA Kits) (NT-proBNP) are common in patients with atrial fibrillation and independently related to increased risks of stroke and mortality.
Elevated post-operative troponin 1 levels predict long-term mortality in older patients undergoing emergency orthpedic surgery.
troponin I phosphorylation has a role in protein kinase C (show PKC ELISA Kits)-mediated enhanced contractile performance of myocytes
MEF2 (show MEF2A ELISA Kits) activation of the troponin I slow enhancer is repressed by hMusTRD1alpha1 (show GTF2IRD1 ELISA Kits)
Low expression of ssTnI was found in 60% of patients in sinus rhythm or paroxysmal AF and in 8% of patients with chronic AF. Relative ssTnI mRNA expression was significantly lower in patients with AF than in those in sinus rhythm.
A biological marker of myocardial injury, but may also be increased after a grand mal (show MAL ELISA Kits) seizure.
These results suggest that this R21C mutation in TnI affects the Ca(2+)-sensitizing effect of Tn, the ability of TnI to be readily phosphorylated by PKA and the stability of TnI to calpain.
analysis of expression profiling of porcine troponin I family in three different types of muscles during development
Two novel single nucleotide polymorphisms (EU743939:g.5174T>C in intron 4 and EU743939:g.8350C>A in intron 7) in TNNI1 and one SNP (EU696779:g.1167C>T in intron 3) in TNNI2 (show TNNI2 ELISA Kits) were identified.
data demonstrate that thyroid hormone (show PTH ELISA Kits) can alter the time course of ssTnI gene expression in cultured cardiac myocytes and TnI (show TNNI2 ELISA Kits) gene regulation is also controlled by some unknown programmed events inside of cardiac myocytes
a localized N-terminal region of TnI comprised of amino acids 33-80, which interacts with C-terminal regions of cTnC and cTnT, is of particular significance in transducing signaling of thin filament activation by strong cross-bridges
K+-depolarization increased Tnni1 and Acta1 (show ACTA1 ELISA Kits) mRNA levels in both differentiated C2C12 and rat skeletal muscle cells in primary culture
the up-stream domain ( approximately 1,800 bp) of mouse fetal TnI (show TNNI2 ELISA Kits) gene is been cloned and characterized
Phosphorylation of troponin I was significantly reduced in Galphaq (show GNAQ ELISA Kits)-overexpressing mice compared to wild type.
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
troponin I, slow skeletal muscle
, troponin I, slow-twitch isoform
, Troponin I, slow isoform
, troponin I, skeletal, slow 1