Tryptase alpha/beta 1 Proteins (TPSAB1)

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Additionally we are shipping Tryptase alpha/beta 1 Antibodies (106) and Tryptase alpha/beta 1 Kits (61) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TPSAB1 7177 Q15661 , P20231
TPSAB1 54271 P27435
TPSAB1 100503895 Q02844
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Top Tryptase alpha/beta 1 Proteins at

Showing 10 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
HOST_Escherichia coli (E. coli) Wild boar His tag,GST tag 100 μg Log in to see 15 to 18 Days
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
HOST_Escherichia coli (E. coli) Dog His tag 100 μg Log in to see 15 to 18 Days
HOST_Mammalian Cells Human His tag   10 μg Log in to see 4 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

TPSAB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
Rat (Rattus) ,

Mouse (Murine) ,

Top referenced Tryptase alpha/beta 1 Proteins

  1. Human TPSAB1 Protein expressed in Escherichia coli (E. coli) - ABIN1098685 : Marquardt, Zettl, Huber, Bode, Sommerhoff: The crystal structure of human alpha1-tryptase reveals a blocked substrate-binding region. in Journal of molecular biology 2002 (PubMed)
    Show all 2 references for 1098685

More Proteins for Tryptase alpha/beta 1 (TPSAB1) Interaction Partners

Human Tryptase alpha/beta 1 (TPSAB1) interaction partners

  1. this study shows that active cow's milk-induced enterocolitis syndrome children have higher serum tryptase levels compared to resolved disease

  2. CD3 (show CD3 Proteins) showed a positive correlation with tryptase and microvascular density, while multiple regression analysis efficaciously predicted microvascular density depending on CD3 (show CD3 Proteins) and tryptase as predictors, supporting a complex interplay between these cells in sustaining tumor angiogenesis in Diffuse large B cell lymphoma patients.

  3. We found the determination of serum tryptase levels over time to be a reassuring correlate of clinical improvement in pediatric mastocytosis

  4. Elevated serum tryptase and ET-1 may be markers of increased coronary instability; some cytokines may be related to the extension of CAD.

  5. these data suggest that the expression of tryptase is regulated by SCF (show KITLG Proteins)/C-KIT signaling via the ERK1/2 and p38MAPK (show MAPK14 Proteins) pathways.

  6. Urine tryptase beta was increased in patients with chronic prostatitis/chronic pelvic pain syndrome compared to controls.

  7. Results demonstrated serum tryptase levels in colo-rectal cancer (CRC (show CALR Proteins)) patients before radical surgical resection.

  8. Circulating tryptase level is associated to obesity related parameters and has a close relation with various metabolic risk factors for subclinical atherosclerosis

  9. Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma.

  10. The best criterion for discriminating IgE- and non IgE-mediated hypersensitivity reactions in anaesthesia was a tryptase value exceeding twice the basal one.

Mouse (Murine) Tryptase alpha/beta 1 (TPSAB1) interaction partners

  1. Following TNFalpha (show TNF Proteins) treatment, increased elastase and tryptase modify the balance between activation and deactivation, elevating active chemerin (show RARRES2 Proteins) concentration in adipocyte media and subsequent CMKLR1 (show CMKLR1 Proteins) activation.

  2. transcriptional activation of mouse mast cell Protease-7 by activin and transforming growth factor-beta is inhibited by microphthalmia-associated transcription factor (show MITF Proteins)

  3. Because mMCP-6 and mMCP-7 can compensate for each other in this mouse disease model, the elimination of both tryptases is necessary to reveal the prominent roles of these serine proteases in joint inflammation and destruction.

  4. TGF-beta stimulates mmcp-7 transcription through the Smad3-Smad4 pathway as well as c-fos induction

Tryptase alpha/beta 1 (TPSAB1) Protein Profile

Protein Summary

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells\; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Gene names and symbols associated with Tryptase alpha/beta 1 Proteins (TPSAB1)

  • tryptase alpha/beta 1 (tpsab1)
  • tryptase (MCT7)
  • tryptase (LOC100049001)
  • tryptase (TRYPTASE-1)
  • tryptase alpha/beta 1 (TPSAB1)
  • tryptase alpha/beta 1 (Tpsab1)
  • tryptase-2 (LOC100144429)
  • tryptase-like (LOC100146737)
  • Mcp-7 protein
  • Mcp7 protein
  • Mcpt7 protein
  • MMCP-7 protein
  • PMCT7 protein
  • rMCP-7 protein
  • TPS1 protein
  • TPS2 protein
  • tpsab1 protein
  • TPSB1 protein

Protein level used designations for Tryptase alpha/beta 1 Proteins (TPSAB1)

tryptase alpha/beta 1 , mast cell alpha II tryptase , mast cell beta I tryptase , tryptase I , tryptase alpha II , tryptase alpha-1 , tryptase alpha/beta-1 , tryptase beta 1 , tryptase beta I , tryptase beta-1 , tryptase-1 , tryptase-I , tryptase-III , MMCP-7 , mast cell protease 7 , tryptase , tryptase, skin , mast cell-restricted serine protease 7

497002 Xenopus (Silurana) tropicalis
397389 Sus scrofa
100049001 Canis lupus familiaris
443433 Ovis aries
7177 Homo sapiens
54271 Rattus norvegicus
100503895 Mus musculus
100144429 Ovis aries
100146737 Equus caballus
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