Vasohibin 1 Proteins (VASH1)

Angiogenesis inhibitor. Additionally we are shipping Vasohibin 1 Antibodies (67) and Vasohibin 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VASH1 22846 Q7L8A9
Mouse VASH1 VASH1 238328 Q8C1W1
Rat VASH1 VASH1 503052  
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Top Vasohibin 1 Proteins at

Showing 4 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 11 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

VASH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

Top referenced Vasohibin 1 Proteins

  1. Human VASH1 Protein expressed in Wheat germ - ABIN1324915 : Shirasuna, Kobayashi, Nitta, Nibuno, Sasahara, Shimizu, Bollwein, Miyamoto: Possible action of vasohibin-1 as an inhibitor in the regulation of vascularization of the bovine corpus luteum. in Reproduction (Cambridge, England) 2012 (PubMed)

More Proteins for Vasohibin 1 (VASH1) Interaction Partners

Human Vasohibin 1 (VASH1) interaction partners

  1. Studied angiogenic activity of vasohibin-1 (VASH1), by analyzing levels of VASH1 in both RCC (show XRCC1 Proteins) tissue and non-neoplastic kidney tissue. Found elevated VASH1 density, but not microvascular density, was a significant and independent predictor of overall survival in RCC (show XRCC1 Proteins).

  2. identified a novel UPS regulatory system in which essential domain architecture (VASH-PS) of VASHs, comprising regions VASH191-180 and VASH280-169 , regulate the cytosolic punctate structure formation in the absence of SVBP.

  3. replicative senescence, the downregulation of VASH1 expression in endothelial cells was caused, at least in part, by the alteration of microRNA expression.

  4. VASH1 expression is associated with tumour progression and may be useful as a prognostic marker of head and neck squamous cell carcinoma

  5. VASH1 expression inhibited tumor vascularization and growth, not only in high VEGF (show VEGFA Proteins)-producing cells, but also in high PDGF (show PDGFA Proteins)-producing cells, reduced their peritoneal dissemination and ascites, and prolonged the survival time of the host

  6. in this study, the length of tube forming structures of endothelial cells in vitro showed that Vasohibin-1 expression in gastric cancer cells significantly decreased the ability of vessel formation of endothelium cells.

  7. These results indicate that cancer cells proteolytically inactivate VASH1 protein secreted by ECs in the tumour microenvironment

  8. VASH1 exerts an antitumor effect on ovarian cancer by inhibiting angiogenesis in the tumor environment

  9. VASH1 expression levels in atheroma reflects both enhanced neovascularization and the inflammatory burden

  10. Knockdown of VASH1 in cancer cells promoted cell growth, adhesion and migration in vitro, and enhanced tumorigenesis and metastasis in vivo.

Mouse (Murine) Vasohibin 1 (VASH1) interaction partners

  1. replicative senescence, the downregulation of VASH1 expression in endothelial cells was caused, at least in part, by the alteration of microRNA expression.

  2. These results indicate that cancer cells proteolytically inactivate VASH1 protein secreted by ECs in the tumour microenvironment

  3. Unaffected fibrosis and angiogenesis seen by knocking out endogenous vasohibin-1.

  4. endogenous VASH1 may regulate the development of diabetic renal alterations

  5. VASH1 and VASH2 (show VASH2 Proteins) showed distinctive localization and opposing function on the fetoplacental vascularization.

  6. PKCdelta (show PKCd Proteins) deficiency enhances neointimal formation, which is associated with delayed reendothelialization and involves increased cellular vasohibin-1 accumulation.

  7. vasohibin1 is the first known intrinsic factor (show GIF Proteins) having broad-spectrum antilymphangiogenic activity

  8. These results suggest a role for VASH1 in negative feedback regulation of haematopoietic progenitors proliferation during recovery following bone marrow ablation.

  9. Loss of vasohibin-1 is associated with persistent angiogenesis in the termination zone of endothelial cells.

  10. These results suggest that endogenous vasohibin-1 is involved in tumor angiogenesis and exogenous vasohibin-1 blocks sprouting angiogenesis by tumors, matures the remaining vessels, and enhances the antitumor effect of conventional chemotherapy

Cow (Bovine) Vasohibin 1 (VASH1) interaction partners

  1. results demonstrate expression of VASH1, especially in blood vascular endothelial cells in the corpus luteum (CL) and show VASH1 inhibits VEGFA (show VEGFA Proteins)-stimulated capillary like-tube formation by luteal endothelial cells and lymphatic endothelial cells vitro; results indicate VASH1 may act as a negative feedback regulator of angiogenesis and lymphangiogenesis in the CL

Vasohibin 1 (VASH1) Protein Profile

Protein Summary

Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.

Gene names and symbols associated with Vasohibin 1 Proteins (VASH1)

  • vasohibin 1 (VASH1)
  • vasohibin 1 (vash1)
  • vasohibin 1 (LOC100358035)
  • vasohibin 1 (Vash1)
  • AI834978 protein
  • D930046M13Rik protein
  • G630009D10Rik protein
  • KIAA1036 protein
  • RGD1564082 protein

Protein level used designations for Vasohibin 1 Proteins (VASH1)

vasohibin 1 , vasohibin-1-like , vasohibin-1

100051887 Equus caballus
423369 Gallus gallus
467514 Pan troglodytes
703906 Macaca mulatta
100216209 Xenopus (Silurana) tropicalis
100358035 Oryctolagus cuniculus
100397672 Callithrix jacchus
100435809 Pongo abelii
22846 Homo sapiens
238328 Mus musculus
503052 Rattus norvegicus
490799 Canis lupus familiaris
615419 Bos taurus
100511141 Sus scrofa
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