Von Willebrand Factor Proteins (VWF)

The glycoprotein encoded by VWF functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. Additionally we are shipping VWF Antibodies (510) and VWF Kits (96) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VWF 7450 P04275
VWF 116669  
VWF 22371 Q8CIZ8
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Top VWF Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_CHO Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$688.00
Details
HOST_Escherichia coli (E. coli) Wild boar His tag 100 μg Log in to see 15 to 18 Days
$784.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$608.00
Details
HOST_Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$460.85
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$560.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,201.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
HOST_Human Human Un-conjugated   100 μg Log in to see 6 to 8 Days
$813.93
Details

VWF Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Rat (Rattus) ,

Mouse (Murine)

Top referenced VWF Proteins

  1. Human VWF Protein expressed in CHO Cells - ABIN2003667 : Nogami, Shima, Nishiya, Hosokawa, Saenko, Sakurai, Shibata, Suzuki, Tanaka, Yoshioka: A novel mechanism of factor VIII protection by von Willebrand factor from activated protein C-catalyzed inactivation. in Blood 2002 (PubMed)
    Show all 4 references for 2003667

More Proteins for Von Willebrand Factor (VWF) Interaction Partners

Human Von Willebrand Factor (VWF) interaction partners

  1. both in acute and chronic cerebrovascular disease patients, ADAMTS13 (show ADAMTS13 Proteins) levels were significantly decreased, with the lowest ADAMTS13 (show ADAMTS13 Proteins) levels found in acute stroke patients. This difference was even more distinct when the ratio of VWF:ADAMTS13 was considered. These results demonstrate the potentially important involvement of the VWF/ADAMTS13 (show ADAMTS13 Proteins) axis in ischemic stroke.

  2. Erythrocyte retention in venous thrombi is mediated by erythrocyte-VWF or erythrocyte-VWF-fibrin interactions.

  3. A novel single-domain antibody against von Willebrand factor A1 domain that interferes with VWF-platelet interactions in vivo. By using this sdAb, show that the A1 domain is pertinent to the participation of VWF in the inflammatory response.

  4. Of special importance is the sequential formation of disulfide bonds with different functions in structural support of VWF multimers, which are packaged, stored and further processed after secretion. Here, all these processes are being reviewed in detail including background information on the occurring biochemical reactions. [review]

  5. A subgroup of patients with end-stage heart failure already suffers AvWS preoperatively. In both CF-LVAD groups, AvWS begins immediately after surgery. Intraoperative vWF:ratios <0.7 correlate with higher incidences of pericardial tamponade and re-operation. The presumably dilutive effect of the heart lung machine on vWF vanishes immediately at the end of surgery, possibly as part of an acute-phase response

  6. this studies show binding of VWF to C1q and thus a direct interaction between starter molecules of hemostasis and the classical pathway of complement

  7. Elevated endothelium-related mediators (vWF, E-selectin (show SELE Proteins) and EPCR (show PROCR Proteins)) appear to participate in the development of pancreatic necrosis and may be a potential indicator of overall prognosis.

  8. Plasma vWF levels are associated with tissue fibrosis in patients undergoing cardiac surgery and with post-surgical atrial fibrillation development in ischaemic patients.

  9. a new role for AP-1 (show FOSB Proteins) in the basolateral constitutive secretion of VWF.

  10. Low ADAMTS-13 (show ADAMTS13 Proteins) levels correlated with high levels of NTproBNP but had no independent prognostic significance. In conclusion, high VWF:Ag levels, probably representing endothelial dysfunction, are associated with prognosis in patients with AL amyloidosis, independently of other features of the disease or cardiac biomarkers.

Pig (Porcine) Von Willebrand Factor (VWF) interaction partners

  1. alterations in glycosylation of vWF and other adhesion proteins associated with the targeting of the alpha1,3-Gal (show GAL Proteins)-epitope in mutant swine may have salutatory effects on the primate platelet activation observed in these xenografts.

Cow (Bovine) Von Willebrand Factor (VWF) interaction partners

  1. Hemodynamic activation of vWF and increased plasma ADAMTS-13 (show ADAMTS13 Proteins) may have contributed to reduced high-molecular-weight vWF multimers and impairment of the vWF-platelet aggregation pathway during mechanical circulatory support.

  2. both the gpIb-VWF interaction and the integrin alpha(2 (show ITGA2 Proteins))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Proteins))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF is bound

Mouse (Murine) Von Willebrand Factor (VWF) interaction partners

  1. A novel single-domain antibody against von Willebrand factor A1 domain that interferes with VWF-platelet interactions in vivo. By using this sdAb, show that the A1 domain is pertinent to the participation of VWF in the inflammatory response.

  2. These experiments delineate an unexpected pathway in which microbiota-triggered TLR2 signaling alters the synthesis of proadhesive VWF by the liver endothelium and favors platelet integrin-dependent thrombus growth.

  3. ADAMTS13 (show ADAMTS13 Proteins) controls vascular remodeling by modifying VWF reactivity during stroke recovery.

  4. these novel findings support the hypothesis that conformation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF in vivo.

  5. results revealed localized vascular expression of FVIII (show F8 Proteins) and von Willebrand factor and identified lymphatic endothelial cell as a major cellular source of FVIII (show F8 Proteins) in extrahepatic tissues.

  6. Endothelial cell derivedVWF is the major determinant that mediates VWF-dependent ischemic stroke by promoting postischemic thrombo-inflammation.

  7. VWF deficiency reduces the progression of liver fibrosis, suggesting a mechanistic role of elevated plasma VWF levels in cirrhosis

  8. von Willebrand factor exerts beneficial effects in a mouse sepsis model via recruitment of neutrophils to inflammatory sites.

  9. Staphylococcus lugdunensis binds directly to von Willebrand factor, which proved to be vital for withstanding shear forces and for its adhesion to the vessel wall and cardiac valves.

  10. Clinical experimental cerebral malaria progression was delayed, and overall survival was significantly prolonged in VWF(-/-) mice compared with WT controls.

VWF Protein Profile

Protein Summary

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.

Gene names and symbols associated with Von Willebrand Factor Proteins (VWF)

  • von Willebrand factor (VWF)
  • von Willebrand factor (vwf)
  • von Willebrand factor (Vwf)
  • Von Willebrand factor homolog (Vwf)
  • 6820430P06Rik protein
  • AI551257 protein
  • B130011O06Rik protein
  • C630030D09 protein
  • F8VWF protein
  • si:ch1073-474e24.1 protein
  • VWD protein
  • VWF protein

Protein level used designations for Von Willebrand Factor Proteins (VWF)

von Willebrand factor , coagulation factor VIII VWF

GENE ID SPECIES
451773 Pan troglodytes
493760 Felis catus
570643 Danio rerio
619381 Monodelphis domestica
722019 Macaca mulatta
7450 Homo sapiens
116669 Rattus norvegicus
399544 Canis lupus familiaris
100009165 Oryctolagus cuniculus
399543 Sus scrofa
280958 Bos taurus
100732530 Cavia porcellus
419031 Gallus gallus
101110931 Ovis aries
22371 Mus musculus
Selected quality suppliers for VWF Proteins (VWF)
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