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WD Repeat Domain 5 (WDR5) ELISA Kits

WDR5 encodes a member of the WD repeat protein family. Additionally we are shipping WDR5 Antibodies (91) and WDR5 Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human WDR5 WDR5 11091 P61964
Anti-Mouse WDR5 WDR5 140858 P61965
Anti-Rat WDR5 WDR5 362093 Q498M4
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More ELISA Kits for WDR5 Interaction Partners

Xenopus laevis WD Repeat Domain 5 (WDR5) interaction partners

  1. The WDR5 is essential for vertebrate development, in that WDR5-depleted X. laevis tadpoles exhibit a variety of developmental defects and abnormal spatial Hox (show MSH2 ELISA Kits) gene expression.

Human WD Repeat Domain 5 (WDR5) interaction partners

  1. WDR5 over-expression is associated with poor breast cancer clinical outcome.

  2. Results identify WDR5 as a key cofactor for N-Myc (show MYCN ELISA Kits)-regulated transcriptional activation and tumorigenesis and as a novel therapeutic target for MYCN (show MYCN ELISA Kits)-amplified neuroblastomas.

  3. BIG3 may block the KPNAs (KPNA1 (show KPNA1 ELISA Kits), KPNA5 (show KPNA5 ELISA Kits), and KPNA6 (show KPNA6 ELISA Kits)) binding region(s) of PHB2 (show PHB2 ELISA Kits).

  4. solution structures of the MLL3 core complex assembled with and without WDR5 by small angle x-ray scattering show similar overall topologies

  5. Target gene recognition by MYC (show MYC ELISA Kits) depends on its interaction with WDR5. This interaction could create an avidity-based chromatin recognition mechanism allowing MYC (show MYC ELISA Kits) to select its target genes in response to both genetic and epigenetic determinants. Review.

  6. we have discovered that WDR5 plays an important role in bladder cancer suggesting that WDR5 is a potential biomarker and a promising target in the treatment of bladder cancer.

  7. Wdr5-MLL (show MLL ELISA Kits) interaction in C/EBPA (show CEBPA ELISA Kits) N-terminal leukemia is a promising pharmacological target.

  8. findings prove that the TSP-1 (show THBS1 ELISA Kits)/CD47 (show CD47 ELISA Kits)/SIRP (show SIRPA ELISA Kits)-alpha signal axis is important to the evolution of tumor cells in the microenvironment of immunotherapy and identify thrombospondin-1 (show THBS1 ELISA Kits) as a key signal

  9. results identify WDR5 as a critical epigenomic integrator of histone phosphorylation and methylation and as a major driver of androgen-dependent prostate cancer cell proliferation

  10. BIG3(WRD5)-PHB2 (show PHB2 ELISA Kits) interaction is critical for the tamoxifen resistance of breast cancer cells; its targeting reverses the resistance.

Mouse (Murine) WD Repeat Domain 5 (WDR5) interaction partners

  1. Wdr5 suppression also reduced IFNgamma, Il-1beta (show IL1B ELISA Kits), and TNFalpha (show TNF ELISA Kits) induced chemokine (show CCL1 ELISA Kits) gene expression in b-cells without affecting islet-cell survival or b-cell function after 48hrs, but did begin to increase islet-cell apoptosis

  2. results suggest that specific RNAs are integral inputs into the WDR5-MLL (show MLL ELISA Kits) complex for maintenance of the active chromatin state and embryonic stem cell fates

  3. Data show that broad association of myc proto-oncogene protein MYC (show MYC ELISA Kits) with chromatin depends on interaction with the WD40 (show DCAF12L2 ELISA Kits)-repeat protein WDR5.

  4. BIG3 inhibits insulin (show INS ELISA Kits) granule biogenesis and insulin (show INS ELISA Kits) secretion.

  5. BIG3 negatively regulates insulin (show INS ELISA Kits) granule exocytosis by restricting insulin (show INS ELISA Kits) granule biogenesis without the release kinetics of individual granules at the final exocytotic steps being affected.

  6. Depletion of KAT2B (show KAT2B ELISA Kits) or WDR5 decreased gluconeogenic gene expression.

  7. analysis of a novel mechanism for epigenetic control of SMC (show DYM ELISA Kits)-marker gene expression during development through interaction of WDR5, homeodomain proteins, and chromatin remodeling enzymes

  8. Study shows that WD repeat domain 5 (Wdr5), a core member of the mammalian Trithorax (trxG) complex, positively correlates with the undifferentiated state and is a regulator of ES cell self-renewal.

  9. Characterization of a novel WDR5-binding site that recruits RbBP5 (show RBBP5 ELISA Kits) through a conserved motif to enhance methylation of histone H3 (show HIST3H3 ELISA Kits) lysine 4 by mixed lineage leukemia protein-1.

  10. WDR5 is essential in assembling a virus-induced VISA (show MAVS ELISA Kits)-associated complex and plays an important role in virus-triggered induction of type I interferons.

WDR5 Antigen Profile

Antigen Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with WD Repeat Domain 5 (WDR5) ELISA Kits

  • WD repeat domain 5 (wdr5) antibody
  • WD repeat domain 5 (wdr5-a) antibody
  • WD repeat domain 5 (wdr5-b) antibody
  • WD repeat domain 5 (WDR5) antibody
  • WD repeat domain 5 (Wdr5) antibody
  • 2410008O07Rik antibody
  • AA408785 antibody
  • AA960360 antibody
  • Big antibody
  • Big-3 antibody
  • MGC80538 antibody
  • MGC81485 antibody
  • SWD3 antibody
  • wdr5-a antibody
  • wdr5-b antibody
  • wu:fk47f04 antibody
  • xwdr5 antibody
  • zgc:56591 antibody
  • zgc:76895 antibody

Protein level used designations for WD Repeat Domain 5 (WDR5) ELISA Kits

WD repeat domain 5 , WD repeat-containing protein 5 , BMP2-induced 3-kb gene protein , SWD3, Set1c WD40 repeat protein, homolog , WD-repeat protein 5 , WD repeat-containing protein BIG-3

GENE ID SPECIES
406372 Danio rerio
446809 Xenopus laevis
447447 Xenopus laevis
496891 Xenopus (Silurana) tropicalis
11091 Homo sapiens
140858 Mus musculus
362093 Rattus norvegicus
100125836 Bos taurus
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