YTH Domain Containing 1 Proteins (YTHDC1)

binds nuclear transcriptosomal complex scaffold attachment factor B (SAF-B) and Sam68\; may play a role in splice site selection and alternative splicing [RGD, Feb 2006].. Additionally we are shipping YTHDC1 Antibodies (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse YTHDC1 YTHDC1 231386  
YTHDC1 91746 Q96MU7
YTHDC1 170956 Q9QY02
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Top YTHDC1 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

YTHDC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Rat (Rattus)

More Proteins for YTH Domain Containing 1 (YTHDC1) Interaction Partners

Human YTH Domain Containing 1 (YTHDC1) interaction partners

  1. Results show that YTHDC1 promotes exon inclusion in targeted mRNAs through recruiting pre-mRNA splicing factor (show SNRPB Proteins) SRSF3 (show SRSF3 Proteins) while blocking SRSF10 (show SRSF10 Proteins) mRNA binding.

  2. The YTHDC1-binding sites and biochemical experiments, not only reveal the specific mode of m(6)A-YTH binding but also explain the preferential recognition of the GG(m(6)A)C sequences by YTHDC1.

  3. Hypoxia induces a specific switch in YT521 expression pattern towards the two non-protein coding mRNA variants, the already characterized isoform 3 and the newly discovered exon 8-skipping isoform.

  4. Studied mRNA levels of FOXO1 (show FOXO1 Proteins), KLF9 (show KLF9 Proteins) and YT521 in human normal and cancerous endometrial tissue. A remarkable (not significant, p = 0.069) increase was found in the YT521 mRNA level of patients' endometrial tissue in comparison with the control subjects.

  5. Lack of YT521 protein is associated with endometrial cancer.

  6. YT521-B has a role in a gene expression in the pathogenesis of Emery-Dreifuss muscular dystrophy

  7. phosphorylation causes sequestration of YT521-B in an insoluble nuclear form, which is unable to change splice sites

YTHDC1 Protein Profile

Protein Summary

binds nuclear transcriptosomal complex scaffold attachment factor B (SAF-B) and Sam68\; may play a role in splice site selection and alternative splicing

Gene names and symbols associated with YTHDC1

  • YTH domain containing 1 (Ythdc1)
  • YTH domain containing 1 (YTHDC1)
  • YTH domain containing 1 (ythdc1)
  • A730098D12Rik protein
  • C80342 protein
  • DKFZp459L1228 protein
  • MGC89461 protein
  • MGC137509 protein
  • mKIAA1966 protein
  • Yt521 protein
  • YT521-B protein
  • zgc:101592 protein

Protein level used designations for YTHDC1

YTH domain containing 1 , splicing factor YT521-B , YTH domain-containing protein 1 , putative splicing factor YT521 , RA301-binding protein

231386 Mus musculus
422656 Gallus gallus
461291 Pan troglodytes
475161 Canis lupus familiaris
492769 Danio rerio
493483 Xenopus (Silurana) tropicalis
495129 Xenopus laevis
613858 Bos taurus
709717 Macaca mulatta
100066303 Equus caballus
100172720 Pongo abelii
100547260 Meleagris gallopavo
100559868 Anolis carolinensis
91746 Homo sapiens
170956 Rattus norvegicus
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