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The encoded gene product presumably interacts with YY1 protein\; however, its exact function is not known. Additionally we are shipping YY1AP1 Antibodies (10) and many more products for this protein.
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activates YAP (show YAP1 Proteins) and stimulates cancer cell growth. Knockdown of ERBB3 (show ERBB3 Proteins) or HBEGF (show HBEGF Proteins) eliminates YAP (show YAP1 Proteins) effects on cell growth and transformation
YY1AP1 may serve as a key molecular target for EpCAM (show EPCAM Proteins)(+) AFP (show AFP Proteins)(+) HCC (show FAM126A Proteins) subtype
we report that YAP (show YAP1 Proteins) and its downstream transcriptional targets CCN1 (show CCNA2 Proteins) and CCN2 (show CTGF Proteins) are markedly elevated in keratinocytes in human skin basal cell carcinoma
knowledge of how YAP (show YAP1 Proteins) and TAZ (show TAZ Proteins) function as mechanosensors and mechanotransducers
F-Actin, assembled in response to Galpha12/13 induced RhoA (show RHOA Proteins)-GTP (show AK3 Proteins), promotes dephosphorylation and activation of the YAP (show YAP1 Proteins) oncogene (show RAB1A Proteins).
Study reports that physical and architectural features of a multicellular sheet inform cells about their proliferative capacity through mechanical regulation of YAP (show YAP1 Proteins) and TAZ (show TAZ Proteins), known mediators of Hippo signaling and organ growth. YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins) activity is confined to cells exposed to mechanical stresses.
The expression of YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins) and ECM (show MMRN1 Proteins)-related-genes is impacted on physiologically relevant substrates. YAP (show YAP1 Proteins) was upregulated in cells on softer substrates.
Studies indicate that the transcriptional co-activators YAP (show YAP1 Proteins) and TAZ (show TAZ Proteins) recently emerged as key mediators of the biological effects that are observed in response to extracellular matrix (ECM (show MMRN1 Proteins)) elasticity and cell shape.
Data suggest that defective expression of LATS2 is attributable to FOXP3 (show FOXP3 Proteins) defects and may be a major independent determinant of YAP (show YAP1 Proteins) protein elevation in cancer.
YY1AP is a novel co-activator of YY1 (show YY1 Proteins)
The encoded gene product presumably interacts with YY1 protein\; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms.
YY1-associated protein 1
, YY1 associated protein 1
, Dingo protein
, hepatocellular carcinoma susceptibility protein
, hepatocellular carcinoma-associated protein 2