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May be involved in transcriptional regulation.. Additionally we are shipping ZNF224 Antibodies (33) and many more products for this protein.
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Data show that Wilms' tumor 1 (show WT1 Proteins) protein (WT1 (show WT1 Proteins))binds to the zinc finger protein 224 (ZNF224) promoter and represses ZNF224 expression.
ZNF224 acts in fine tuning of WT1 (show WT1 Proteins)-dependent control of gene expression, acting as a co-activator of WT1 (show WT1 Proteins) in the regulation of proapoptotic genes and suppressing WT1 (show WT1 Proteins) mediated transactivation of antiapoptotitc genes.
REVIEW: ZNF224 is a multifunctional protein and alternative splicing, sub-cellular compartmentalization and isoform-specific interactions may modulate its activity
ZNF224 acts as a transcriptional co-regulator of WT1 (show WT1 Proteins).
Coimmunoprecipitation and immunocytochemistry revealed that DEPDC1 (show DEPDC1 Proteins) interacted and colocalized with zinc finger transcription factor (show OSR1 Proteins) ZNF224, a known transcriptional repressor.
Results suggest that bone marrow zinc finger 2 (BMZF2) interferes with the transactivation potential of Wilms tumor suppressor gene (WT1 (show WT1 Proteins)).
We demonstrate that ZNF224, a Kruppel-like zinc finger transcription factor, is the repressor protein that specifically binds to the negative cis-element AldA-NRE and affects the AldA-NRE-mediated transcription
Differential expression and cellular localization of ZNF224 and ZNF255, two isoforms of the Kruppel-like zinc-finger protein family.
CIC silencer activity extends over 26 bp (-595/-569), which specifically bind a protein ZNF224 present in HepG2 cell nuclear extracts.
ZNF224 recruits the arginine methyltransferase PRMT5 on the transcriptional repressor complex of the aldolase A gene
May be involved in transcriptional regulation.
bone marrow zinc finger 2
, zinc finger 2, bone marrow
, zinc finger protein 233
, zinc finger protein 255
, zinc finger protein 27 (KOX 22)
, zinc finger protein KOX22
, zinc finger protein ZNF255
, protein mKR4