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Zinc Finger Protein 36, C3H Type, Homolog (Mouse) Proteins (ZFP36)

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Additionally we are shipping ZFP36 Antibodies (76) and ZFP36 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse ZFP36 ZFP36 67150 Q99MB7
ZFP36 7538 P26651
Rat ZFP36 ZFP36 79426 P47973
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Top ZFP36 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days

ZFP36 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaction Partners

Mouse (Murine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. Zinc Finger Protein 36 (show ZKSCAN1 Proteins) deficiency has profound effects on the splenic transcriptome.

  2. Mouse LARP4 is regul (show LARP4 Proteins)ated by TNF-alpha in a TT (show TNF Proteins)P-dependent manner.

  3. Regulation of mRNAs by tristetraprolin appears to function as one of several critical post-transcriptional regulatory mechanisms controlling satellite cell homeostasis.

  4. Tristetraprolin limits inflammatory cytokine production in tumor-associated macrophages in an mRNA decay-independent manner.

  5. Dominant suppression of inflammation can be achieved via targeted mutation of the mRNA destabilizing protein tristetraprolin.

  6. DUSP1 (show DUSP1 Proteins) and tristetraprolin cooperate to regulate macrophage responses to lipopolysaccharide.

  7. data shows TTP not only regulates the primary cellular response to innate immune stimuli, exemplified by TNF (show TNF Proteins) elaborated from macrophages, but also regulates expression of transcripts involved in the secondary response of mesenchymal cells to TNF (show TNF Proteins) stimulation

  8. study provides a novel mechanism for the posttranscriptional regulation of TF expression, indicating that this is selectively regulated by PARP-14.

  9. Systemic inflammation caused by TTP deficiency leads to endothelial dysfunction; this process is independent of cholesterol and not mediated by TNF-alpha (show TNF Proteins) solely.

  10. Intermedin (show ADM2 Proteins) attenuates macrophage foam-cell formation via tristetraprolin-mediated degradation of CD36 (show CD36 Proteins) mRNA.

Human Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. Low TTP (show ADAMTS13 Proteins) expression is associated with epithelial-mesenchymal transition in cancer.

  2. PP2A (show PPP2R4 Proteins) activators boost the anti-inflammatory function of TTP (show ADAMTS13 Proteins) and have implications for future pharmacotherapeutic strategies to combat inflammation in respiratory disease.

  3. The mRNA destabilizing activity of TTP (show ADAMTS13 Proteins) was increased when the partially disordered RNA binding domain (RBD (show CACNA1D Proteins)) of TTP (show ADAMTS13 Proteins) was replaced with the fully structured RBD (show CACNA1D Proteins) of TIS11d (show ZFP36L2 Proteins), indicating that differences in the folded state of the RBD (show CACNA1D Proteins) affect the activity of the proteins in the cell.

  4. Tristetraprolin induces cell cycle arrest in breast tumor cells by targeting AP-1/c-Jun (show JUN Proteins) and NF-kappaB (show NFKB1 Proteins)/RelA (show NFkBP65 Proteins) pathway.

  5. TTP (show ADAMTS13 Proteins)-dependent regulatory pathway described herein likely contributes to the role of IL-22 (show IL22 Proteins) in inflammation and cancer and may evolve as novel target for pharmacological IL-22 (show IL22 Proteins) modulation.

  6. Results suggest that miR (show MLXIP Proteins)-29a acts as an oncogene (show RAB1A Proteins) by down regulating TTP (show ADAMTS13 Proteins) and suggest the potential of miR (show MLXIP Proteins)-29a and TTP (show ADAMTS13 Proteins) as biomarkers.

  7. TTP (show ADAMTS13 Proteins) might regulate interleukin (IL)-6 (show IL6 Proteins) and IL-18 (show IL18 Proteins) expression in diabetes. Diabetes with clinical proteinuria is accompanied by decreased urinary and serum level of TTP (show ADAMTS13 Proteins) mRNA and protein, and increased levels of IL-6 (show IL6 Proteins) and IL-18 (show IL18 Proteins) mRNA and protein.

  8. Involvement of LARP4 (show LARP4 Proteins) as a target of TNF-alpha (show TNF Proteins)-TTP regulation provides a clue as to how its functional activity may be used in a physiologic pathway.

  9. Modulation of TAFI (show CPB2 Proteins) levels by pro-inflammatory mediators or lipopolysaccharide involves binding of tristetraprolin to the CPB2 (show CPB2 Proteins) 3'-UTR, which mediates CPB2 (show CPB2 Proteins) mRNA destabilisation.

  10. DUSP1 (show DUSP1 Proteins) overexpression and inhibition of MAPKs prevented IL1B (show IL1B Proteins)-induced expression of ZFP36, this was associated with increased TNF (show TNF Proteins) mRNA expression at 6 h, an effect that was predominantly due to elevated transcription.

Pig (Porcine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. direct interaction between TTP protein and porcine TNF-alpha (show TNF Proteins) mRNA ARE probe

ZFP36 Protein Profile

Protein Summary

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Gene names and symbols associated with ZFP36

  • tristetraproline (EDI_287240)
  • Tristetraproline (Bm1_42085)
  • tristetraproline (LOAG_03119)
  • similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth (ZFP36)
  • zinc finger protein 36, C3H type, homolog (mouse) (ZFP36)
  • ZFP36 ring finger protein (zfp36)
  • ring finger protein 141 (Rnf141)
  • ZFP36 ring finger protein (ZFP36)
  • zinc finger protein 36 (Zfp36)
  • 2610110L04Rik protein
  • AA792898 protein
  • AU022812 protein
  • c3h-1 protein
  • G0S24 protein
  • Gos24 protein
  • Nup475 protein
  • RNF162A protein
  • Tis11 protein
  • TIS11D protein
  • TISII protein
  • Ttp protein
  • Zfp-36 protein
  • ZFP36 protein
  • ZNF230 protein

Protein level used designations for ZFP36

tristetraproline , Tristetraproline , similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth , zinc finger protein 36, C3H type, homolog (mouse) , tristetraprolin , zinc finger protein 36, C3H type, homolog , RING finger protein 141 , zinc finger protein 230 , CCCH zinc finger protein C3H-1 , G0/G1 switch regulatory protein 24 , growth factor-inducible nuclear protein NUP475 , zinc finger protein 36 homolog , zinc finger protein, C3H type, 36 homolog , TTP , zfp-36 , TPA-induced sequence 11 , CCCH (CX8CX5CX3H) zinc finger domain RNA-binding protein , TIS11 , zinc finger protein homologous to Zfp-36 in mouse , TNF alpha inhibitor , Tax interacting protein

5879635 Entamoeba dispar SAW760
6103302 Brugia malayi
9940506 Loa loa
698280 Macaca mulatta
736203 Pan troglodytes
100127733 Xenopus (Silurana) tropicalis
67150 Mus musculus
398102 Xenopus laevis
7538 Homo sapiens
79426 Rattus norvegicus
22695 Mus musculus
484510 Canis lupus familiaris
100316849 Sus scrofa
282127 Bos taurus
443283 Ovis aries
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