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Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Additionally we are shipping ZFP42 Antibodies (117) and ZFP42 Kits (1) and many more products for this protein.
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TGF-beta1 (show TGFB1 Proteins)-induced CK17 (show KRT17 Proteins) enhances cancer stem cell-like properties rather than epithelial-mesenchymal transition in promoting cervical cancer metastasis via the ERK1/2-MZF1 signaling pathway.
SIRT6 (show SIRT6 Proteins) over-expression establishes a condition whereby reconfiguration of the Hexokinase 2 (show HK2 Proteins) promoter chromatin structure makes it receptive to interaction with MZF1/SIRT6 (show SIRT6 Proteins) complex, thereby favouring a regulatory state conducive to diminished transcription
Tumor antigen PRAME (show PRAME Proteins) is up-regulated by MZF1 in cooperation with DNA hypomethylation in melanoma cells.
MZF1 has a role in cellular migration of gastric cancer cells via promoting an increase in intracellular SMAD4 (show SMAD4 Proteins) levels. This study might provide new evidence for the molecular basis of the tumor suppressive effect of the MZF1-SMAD4 (show SMAD4 Proteins) axis, a new therapeutic target in advanced human gastric cancer.
Here we discuss the regulation of MZF1 that mediated its recruitment and activation in cancer, concentrating on posttranslational modification by phosphorylation, and sumoylation
These findings suggest that PKCalpha (show PKCa Proteins) expression in HCC (show FAM126A Proteins) could be stimulated by the formation of MZF-1/Elk-1 (show ELK1 Proteins) complex, which directly binds to the PKCalpha (show PKCa Proteins) promoter.
our results revealed that the loss of nuclear expression of MZF1 in oral squamous cell carcinoma (OSCC) samples can predict the progression of OSCC and the survival of OSCC patients in Taiwan
The aberrant decreases in Ik-1 and MZF1 contribute significantly to the pathogenesis of NPM-ALK(+) T-cell lymphoma through the upregulation of IGF-IR expression.
our results argue that MZF-1 regulates the CTGF and NOV genes in the hematopoietic compartment, and may be involved in their respective functions in the stroma.
Data indicate that elevated miR (show MLXIP Proteins)-492 expression in prostate tumors that resulted in diminished myeloid zinc-finger 1 (MZF-1) and ferroportin (show SLC40A1 Proteins) (FPN).
Data show that zinc finger protein 42 (Rex1) and zinc finger and SCAN domain containing 4D/4C (Zscan4D/4C) correlate with the cell-cycle length under different mechanisms.
Results show that a novel pluripotency regulator, REX1, is essential for pluripotency and reprogramming.
Rex1 plays a role during preimplantation development (show MTA2 Proteins) and alters expression levels of Zscan4 (show ZSCAN4 Proteins).
Results show that Rex1 regulates endogenous retroviral element expression in mouse embryonic stem cells and during pre-implantation development and suggest that Rex1 and its relatives have evolved as regulators of endogenous retroviral transcription.
RNF12 causes REX1 breakdown through dose-dependent catalysis, thereby representing an important pathway to initiate X-chromosome inactivation
the involvement of Rex-1 in control of Polycomb (show CBX2 Proteins) target genes during pluripotency or differentiation.
loss of Rex1 leads to impaired testicular function.
the functional connection of Rex1 to genomic imprinting represents another case where newly made genes have co-evolved with lineage-specific phenomena.
Embryonic stem cell marker Rex-1 and the pluripotent stem cell marker Oct-4 (show POU5F1 Proteins) are spontaneously expressed by untreated mesenchymal stem cells.
Rex1, which is highly expressed in stem cells, inhibits signaling via the Janus kinase (JAK (show JAK3 Proteins))/signal transducer and activator of transcription (STAT (show STAT1 Proteins)) pathway, thereby modulating the differentiation of F9 cells.
Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal.
zinc finger protein 42
, zinc finger and SCAN domain-containing protein 6
, zinc finger protein 42 (myeloid-specific retinoic acid-responsive)
, RNA exonuclease 1 homolog
, elongin A binding protein 1
, elongin A-binding protein 1
, elongin-A-binding protein 1
, transcription elongation factor B polypeptide 3 binding protein 1
, transcription elongation factor B polypeptide 3-binding protein 1
, REX1 transcription factor
, reduced expression protein 1
, zinc finger protein 42 homolog
, zinc finger protein 754