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AFP encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Additionally we are shipping alpha Fetoprotein Antibodies (798) and alpha Fetoprotein Proteins (56) and many more products for this protein.
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Rat (Rattus) alpha Fetoprotein ELISA Kit for Sandwich ELISA - ABIN416096
Mansour, Bekheet, Al-Rejaie, Al-Shabanah, Al-Howiriny, Al-Rikabi, Abdo: Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model. in BioFactors (Oxford, England) 2010
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endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (show CTNNB1 ELISA Kits), suggesting that beta-catenin (show CTNNB1 ELISA Kits) regulates AFP during liver development.
Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.
AFP mRNA and VEGF-C (show VEGFC ELISA Kits) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.
A DEHP treatment-induced phenotype was identified with lack of glycogen (show GYS1 ELISA Kits) accumula-tion and intracytoplasmic localization of beta-catenin (show CTNNB1 ELISA Kits) which was associated with increased AFP gene expression.
The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety
Foxa1 (show FOXA1 ELISA Kits) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements
The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.
AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (show HRAS ELISA Kits) p21 genes
A murine Nkx2.8 was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (show NR5A2 ELISA Kits).
The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (show FOXA1 ELISA Kits)
AFP remained the best single marker, and the combined use of AFP with prothrombin (show F2 ELISA Kits) precursor or DKK-1 (show DKK1 ELISA Kits) had the best diagnostic performance compared to all other possible combinations of the four biomarkers, even in early stage hepatocellular carcinoma.
combination of circulating miR (show MLXIP ELISA Kits)-126 + AFP is a promising noninvasive diagnostic biomarker for HBV-HCC (show FAM126A ELISA Kits) and may be useful in the management of HCC (show FAM126A ELISA Kits) patients.
Suggest that AFP with modified cutoffs according to the individual's hepatitis status might be a useful screening marker for HCC (show FAM126A ELISA Kits) in hepatitis prevalent areas.
Data show that both Ezrin (show EZR ELISA Kits) and SIX1 (show SIX1 ELISA Kits) proteins are highly expressed in alpha fetoprotein-negative hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) and significantly related with the TNM (show ODZ1 ELISA Kits) stage.
When confirmed by a low alpha-fetoprotein concentration (<400 mug/L), CK-19 (show KRT19 ELISA Kits) expression in is an additional valuable indicator of early recurrence, distant metastasis, and poor prognosis in HBV-positive patients
The results of this meta-analysis showed that serum GP73 (show GOLM1 ELISA Kits) + AFP exhibited significantly higher diagnostic accuracy for HCC (show FAM126A ELISA Kits) than did serum GP73 (show GOLM1 ELISA Kits) or AFP alone.
AFP has a role in radiologic response to combined radiotherapy and transarterial chemoembolization for hepatocellular carcinoma with portal vein tumor thrombus
Although circulating serum AFP is known as a growth-enhancing factor (show PLA2G2A ELISA Kits) during development, cytoplasmic AFP has a lethal role in the oncogenesis, growth, and metastasis of adult liver cancer.
Serum levels of AFP, DKK1 (show DKK1 ELISA Kits), and OPN (show SPP1 ELISA Kits) were significantly elevated in patients with hepatocellular carcinoma.
Adding AFP and ascites to the BCLC staging classification can improve prognosis prediction for early and intermediate stages of hepatocellular carcinoma.
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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