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serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) ELISA Kits

SHMT1 encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Additionally we are shipping serine Hydroxymethyltransferase 1 (Soluble) Antibodies (56) and serine Hydroxymethyltransferase 1 (Soluble) Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat SHMT1 SHMT1 287379  
Anti-Human SHMT1 SHMT1 6470 P34896
Anti-Mouse SHMT1 SHMT1 20425 P50431
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More ELISA Kits for serine Hydroxymethyltransferase 1 (Soluble) Interaction Partners

Human serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. an association between MTRR (show MTRR ELISA Kits) 66 and SHMT1 1420 polymorphisms and spaceflight-induced vision changes

  2. our meta-analysis suggested that the SHMT1 C1420T polymorphism was associated with decreased risk of breast cancer.

  3. SHMT1 knockdown in lung cancer cells leads to cell cycle arrest and to p53 (show TP53 ELISA Kits)-dependent apoptosis.

  4. In this meta-analysis, SHMT1 C1420T polymorphism did not have a significant association with the risk of cancer overall.

  5. SHMT1 exists in solution as a tetramer, both in the absence and presence of PLP (show PLP1 ELISA Kits), while SHMT2 (show SHMT2 ELISA Kits) undergoes a dimer-to-tetramer transition.

  6. found evidence for association of SHMT1 C1420T polymorphism with significantly reduced risk of breast cancer in Asians

  7. SHMT1 C1420T polymorphism is not associated with overall cancer development.

  8. serine hydroxymethyltransfarase C1420T reduces risk for both acute lymphoblastic leukemia and acute myeloid leukemia (show BCL11A ELISA Kits) and influences disease progression in acute lymphoblastic leukemia

  9. SHMT1 C1420T and DNMT3B (show DNMT3B ELISA Kits) C46359T polymorphisms are not associated with HNC (show MMP8 ELISA Kits) development in Brazilian population, however, SHMT1 C1420T polymorphism is less frequent in patients with primary site of tumor in larynx

  10. geography-specific effects of the SHMT1 polymorphism that render Europeans susceptible to colorectal caner, but not Americans.

Mouse (Murine) serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. Shmt1 and dietary folate deficiency influence metabolic markers of homocysteine remethylation in mice.

  2. SHMT1 and TYMS (show TYMS ELISA Kits) localization to the nucleus is essential to prevent uracil accumulation in DNA

  3. Data show that Shmt1 hemizygosity was associated with increased risk for intestinal cancer in Apc (show APC ELISA Kits)(min)(/+) mice through a gene-by-diet interaction.

  4. These results provide evidence that disruption of Shmt1 expression causes NTDs by impairing thymidylate biosynthesis and shows that changes in the expression of genes that encode folate-dependent enzymes may be key determinates of NTD risk.

  5. Shmt1 (SHMT1), but not Srr (show SRR ELISA Kits), is likely to be one of the genetic components regulating prepulse inhibition in mice and possibly relevant to human schizophrenia.

  6. mitochondrial SHMT-derived one-carbon units are essential for folate-mediated one-carbon metabolism in the cytoplasm

  7. SHMT1 and SHMT2 (show SHMT2 ELISA Kits) are functionally redundant in nuclear de novo thymidylate biosynthesis

Rabbit serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. we have expressed, characterized, and determined the crystal structures of rabbit cytosolic serine hydroxymethyltransferase T254A and T254C mutant forms, in the absence and presence of substrates.

Arabidopsis thaliana serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) interaction partners

  1. SHM1 and SHM2 operate in a redundant manner in one-carbon metabolism of nonphotorespiring cells with a high demand of one-carbon units.

  2. The senescence is initiated in shm1-1 under photorespiratory conditions. Transcription of the senescence marker SAG12 is enhanced in shm1-1.

  3. Structural modeling of SHM1, SHM2, and SHM4 presented features that may explain the activity differences between the mitochondrial and cytosolic isozymes.

  4. The characterization and expression of SHMT1 in A. thaliana. [SHMT1]

  5. SHM1 expression is required for mitochondrial serine hydroxymethyltransferase (show SHMT2 ELISA Kits) activity and proper function of the C2 cycle during growth in ambient air.

  6. SHMT1 interacts with GLU1 and this interaction is necessary for photorespiratory serine hydroxymethyltransferase (SHMT) activity.

serine Hydroxymethyltransferase 1 (Soluble) (SHMT1) Antigen Profile

Antigen Summary

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with SHMT1

  • serine hydroxymethyltransferase 1 (soluble) (Shmt1) antibody
  • serine hydroxymethyltransferase 1 (soluble) (shmt1) antibody
  • serine hydroxymethyltransferase 1 (soluble) (SHMT1) antibody
  • serine transhydroxymethyltransferase 1 (SHM1) antibody
  • AI324848 antibody
  • AI385541 antibody
  • C81125 antibody
  • CSHMT antibody
  • F20D10.50 antibody
  • F20D10_50 antibody
  • LRRGT00032 antibody
  • MEL-32 antibody
  • MGC53442 antibody
  • mshmt antibody
  • mshmt1 antibody
  • mshmt2 antibody
  • serine transhydroxymethyltransferase 1 antibody
  • SHMT antibody
  • Shmt1 antibody
  • SHMT2 antibody
  • STM antibody
  • zgc:66171 antibody
  • zgc:77524 antibody

Protein level used designations for SHMT1

serine hydroxymethyltransferase, cytosolic , serine hydroxymethyltransferase 1 (soluble) , zSHMT-1 , SHMT , glycine hydroxymethyltransferase , serine methylase , cytoplasmic serine hydroxymethyltransferase , cytosolic serine hydroxymethyltransferase , serine hydroxymethyl transferase , serine hydroxymethyltransferase 2 (mitochondrial)

287379 Rattus norvegicus
380048 Xenopus laevis
394021 Danio rerio
416520 Gallus gallus
454490 Pan troglodytes
489536 Canis lupus familiaris
548668 Xenopus (Silurana) tropicalis
100117303 Nasonia vitripennis
100159628 Acyrthosiphon pisum
100171460 Pongo abelii
100600675 Nomascus leucogenys
6470 Homo sapiens
20425 Mus musculus
100009405 Oryctolagus cuniculus
443544 Ovis aries
509002 Bos taurus
829949 Arabidopsis thaliana
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