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Browse our ENOS Proteins (NOS3)

Full name:
Nitric Oxide Synthase 3 (Endothelial Cell) Proteins (NOS3)
On are 19 Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) Proteins from 7 different suppliers available. Additionally we are shipping ENOS Antibodies (459) and ENOS Kits (96) and many more products for this protein. A total of 588 ENOS products are currently listed.
2310065A03Rik, cNOS, EC-NOS, ecNOS, ENOS, NOS, Nos-3, NOS3, NOSIII
list all proteins Gene Name GeneID UniProt
NOS3 4846 P29474
NOS3 18127 P70313
NOS3 24600 Q62600

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ENOS Proteins (NOS3) by Origin

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More Proteins for ENOS Interaction Partners

Human Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) interaction partners

  1. INOS and eNOS are the main contributors to NOS-dependent sweating.

  2. T-786C in promoter region and 894G-->T at exon 7 of eNOS gene might be genetic predisposal factors associated with risk of osteoporosis in Sichuan region males.

  3. demonstrate Pim1 (show PIM1 Proteins) as a novel kinase that is responsible for the phosphorylation of eNOS at Ser (show SIGLEC1 Proteins)-633 and enhances endothelial cells sprouting of aortic rings from diabetic mice

  4. Overexpression of eNOS restores circulating endothelial progenitor cell function to cells isolated from patients with coronary artery disease.

  5. Human eNOS expression enhances angiogenic responses of bone marrow-derived mesenchymal stem cells.

  6. These results demonstrate that exogenous peptide consisting of cationic amino acids can internalize and enhance the catalytic activity of eNOS via modulation of caveolar signaling and intracellular Ca(2 (show CA2 Proteins)+) release in endothelial cells

  7. endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B') in human arterial smooth muscle cells

  8. Kidneys in eNOS-/- mice have severe defects in vascular perfusion/structure in the renal cortex.

  9. The results indicate that common variants in MnSOD and eNOS increased the risk of T2DM in the Chinese Han population.

  10. Data show that plasma levels of endothelial microparticle (EMP (show MAEA Proteins)) and endothelin-1 (ET-1 (show EDN1 Proteins) are significantly higher in intermediate )lesion group, while their nitric oxide (NO) and nitric oxide synthase 3 (eNOS) are lower.

Pig (Porcine) Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) interaction partners

  1. NOS3 was lowest in kidneys removed from live pigs, greater in kidneys from pigs with brain death, and greatest in kidneys from pigs with cardiac arrest.

  2. Rapid atrial pacing increases ADMA and down-regulates eNOS expression in an ADMA-independent manner.

  3. Icariin and icariside II may increase the eNOS expression through activating EGF-EGFR (show EGFR Proteins) pathway in porcine aortic endothelial cells.

  4. Data suggest that pig sperm contain bNOS (show NOS1 Proteins), iNOS (show NOS2 Proteins), and eNOS; up-regulation of NOS by leptin (show LEP Proteins) during acrosome reaction and inhibition of acrosome reaction by inhibitors of nitric oxide synthases suggests these enzymes are involved in acrosome reaction.

  5. Periodic acceleration (pGz) acutely increases endothelial and neuronal nitric oxide synthase (show NOS1 Proteins) expression in endomyocardium of normal swine.

  6. Data suggest that angiotensin II regulates nNOS and eNOS expression and NOS activity in afferent arterioles of the developing kidney via angiotensin 1 and 2 receptors.

  7. Endothelial nitric oxide synthase mRNA expression was elevated in gestational day 50 intrauterine growth retardation placenta and areola compared to gd50 control.

  8. Oligonol prevented the impairment of eNOS activity induced by high glucose through reversing altered eNOS phosphorylation status.

  9. Exercise training significantly increased total eNOS and phosphorylated levels of eNOS (pSer(1179)) in collateral-dependent arteries of experimental minipigs.

  10. Data show that wall shear stress increases with a decrease in artery diameter; eNOS protein contents decrease with an increase in diameter.

Cow (Bovine) Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) interaction partners

  1. Signals that activate and phosphorylate eNOS are transmitted through distinct membrane domains in endothelial cells. Cholesterol domains, but not individual caveolae, mediate HDL stimulation of eNOS. VEGF and shear stress may act through caveolae.

  2. eNOS serine 1179 phosphorylation, in addition to enhancing NO production, also profoundly affects superoxide generation

  3. In addition to the heme center of eNOS oxygenase domain, we confirmed another O2.- generation site in the eNOS reductase domain and characterized its regulatory properties.

  4. A dimer-destabilized mutant of bovine eNOS where cysteine 101 was replaced by alanine, cloned and introduced into an eNOS-deficient mouse strain and that results provide the first in vivo evidence that eNOS-dependent oxidative stress is unlikely to be an initial cause of impaired endothelium-dependent vasodilation and/or a pathologic factor promoting intimal hyperplasia.

  5. Data show that resveratrol (Res) reversed caveolin-1 (Cav-1 (show CAV1 Proteins))/endothelial nitric oxide synthase (eNOS) expressions in high glucose cultured bovine aortic endothelial cells (BAECs).

  6. Fluorescence decays of fluorescently labeled CaM (show KRIT1 Proteins) bound to eNOS reveal four distinct conformational states and single-molecule fluorescence trajectories show multiple fluorescence states with transitions between states

  7. Endothelial nitric oxide synthase is regulated by ERK (show MAPK1 Proteins) phosphorylation at Ser602.

  8. key regulatory role of CaM (show KRIT1 Proteins) involves the stabilization of structural intermediates and precise positioning of the pivot for the FMN (show FMN1 Proteins) domain tethered shuttling motion to accommodate efficient and rapid electron transfer in the homodimer of eNOS.

  9. radiation-induced eNOS activation in bovine aortic endothelial cells is regulated by ATM (show ATM Proteins) and HSP90 (show HSP90 Proteins)

  10. Heparan sulfate is involved in both centralized and decentralized glycocalyx-mediated mechanotransduction, with GPC1 (show GPC1 Proteins) acting as a centralized agent and SDC1 (show SDC1 Proteins) functioning in decentralized mechanotransmission. GPC1 (show GPC1 Proteins) mediates NOS3 activation.

Rabbit Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) interaction partners

  1. VEGFR2 (show KDR Proteins) activation was not affected by Slit2 (show SLIT2 Proteins), but eNOS phosphorylation was diminished

  2. Data suggest distinct localizations of eNOS at the spiral arteries/arterial sinuses and iNOS (show NOS2 Proteins) along the radial arteries in the developing placenta.

  3. Pulmonary ischaemia-reperfusion up-regulates inducible nitric oxide synthesis and/activity, which coincides with reduced endothelial nitric oxide synthase activity.

  4. eNOS dysregulation may be a central mechanism of impaired cardioprotection during hyperglycemia.

  5. Quercetin inhibited myocardial ischemia-reperfusion-induced NOS3 mRNA and protein expression.

Mouse (Murine) Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) interaction partners

  1. Through the abrogation of NAD(P)H (show NQO1 Proteins) oxidase-driven eNOS uncoupling.

  2. The in vitro concordance of early Nos3(-/-) disease signatures supports the utility of iPSCs as a cellular model of developmental heart defects

  3. Findings do not support the hypothesis that reduced NO production from eNOS contributes to obesity-related adipose tissue inflammation.

  4. Normal and high eNOS levels are detrimental in both mild and severe cardiac pressure-overload.

  5. eNOS may be necessary to maintain podocyte integrity, especially mitochondrial function

  6. Disruption of the eNOS-NO signaling pathway exacerbates peritoneal fibrosis by delaying wound healing.

  7. BMP4 (show BMP4 Proteins) has a role in inducing NOX1 (show NOX1 Proteins)-dependent eNOS uncoupling in T2DM, which may promote development of novel therapeutics restoring endothelial function in T2DM

  8. The eNOS expression was induced with adipocyte differentiation and inhibition of eNOS/NO enhanced lipolysis in vitro and in vivo.

  9. Diet-induced obesity leads to l-arginine (show GATM Proteins) deficiency and eNOS uncoupling in perivascular adipose tissue.

  10. Data show that the transient receptor potential vanilloid type 1 (TRPV1 (show TRPV1 Proteins)) ligand- induced increase in AMP-activated protein kinase (AMPK (show PRKAA2 Proteins)) and nitric oxide synthase type III (eNOS) phosphorylation was markedly lower in TRPV1 (show TRPV1 Proteins)-/- (knockout) than WT aortas.

Guinea Pig Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3) interaction partners

  1. The present evidence indicated that the customary HBOT protocol may increase constitutive NOS expression.

ENOS (NOS3) Protein Profile

Protein Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ENOS (NOS3)

  • nitric oxide synthase 3 (endothelial cell) (NOS3)
  • nitric oxide synthase 3 (endothelial cell) (nos3)
  • endothelial nitric oxide synthase (23B)
  • nitric oxide synthase 3, endothelial cell (Nos3)
  • 2310065A03Rik protein
  • cNOS protein
  • EC-NOS protein
  • ecNOS protein
  • ENOS protein
  • NOS protein
  • Nos-3 protein
  • NOS3 protein
  • NOSIII protein

Protein level used designations for NOS3

nitric oxide synthase 3 (endothelial cell) , nitric oxide synthase, endothelial-like , EC-NOS , NOS type III , NOSIII , cNOS , constitutive NOS , endothelial NOS , nitric oxide synthase, endothelial , eNOS , endothelial nitric oxide synthase , endothelial nitric oxide synthase NOS3 , endothelial nitric oxide synthase 3

714231 Macaca mulatta
100018035 Monodelphis domestica
100486016 Xenopus (Silurana) tropicalis
443077 Ovis aries
4846 Homo sapiens
403784 Canis lupus familiaris
397557 Sus scrofa
287024 Bos taurus
443073 Ovis aries
100063339 Equus caballus
100009498 Oryctolagus cuniculus
18127 Mus musculus
24600 Rattus norvegicus
100135577 Cavia porcellus
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