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anti-Mouse (Murine) Renin Antibodies:
anti-Rat (Rattus) Renin Antibodies:
anti-Human Renin Antibodies:
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Mouse (Murine) Polyclonal Renin Primary Antibody for EIA, IHC (p) - ABIN264819
Carilli, Wallace, Smith, Wong, Lewicki: Semi-preparative purification of recombinant human renin and prorenin. in Journal of chromatography 1989
Show all 2 references for ABIN264819
Human Polyclonal Renin Primary Antibody for ELISA, WB - ABIN1535288
Hardman, Hort, Catanzaro, Tellam, Baxter, Morris, Shine: Primary structure of the human renin gene. in DNA (Mary Ann Liebert, Inc.) 1985
Human Monoclonal Renin Primary Antibody for ELISA, WB - ABIN562625
Salhan, Husain, Subrati, Goyal, Singh, Rai, Malhotra, Singhal: HIV-induced kidney cell injury: role of ROS-induced downregulated vitamin D receptor. in American journal of physiology. Renal physiology 2012
Dog (Canine) Polyclonal Renin Primary Antibody for WB - ABIN2776795
Lavoie, Liu, Bianco, Beltz, Johnson, Sigmund: Evidence supporting a functional role for intracellular renin in the brain. in Hypertension 2006
Human Polyclonal Renin Primary Antibody for IF (p), IHC (p) - ABIN715436
Wanka, Staar, Lutze, Peters, Hildebrandt, Beck, Bäumgen, Albers, Krieg, Zimmermann, Sczodrok, Schäfer, Hoffmann, Peters: Anti-necrotic and cardioprotective effects of a cytosolic renin isoform under ischemia-related conditions. in Journal of molecular medicine (Berlin, Germany) 2015
Results show negative regulation of HDAC1 (show HDAC1 Antibodies) by a Cul3 (show CUL3 Antibodies)-REN (show REN1 Antibodies) E3 ubiquitin ligase (show MUL1 Antibodies) complex.
REN is upregulated by neurogenic signals (retinoic acid, EGF, and NGF) in embryonal stem (ES) cells and neural progenitor cell lines in association with neurotypic differentiation.
REN (show REN1 Antibodies) protein enhances caspase-3 (show CASP3 Antibodies) activation and antagonizes the Shh (show SHH Antibodies) pathway suggesting that this gene may represent a restraint of Shh (show SHH Antibodies) signaling.
Increased plasma renin, AT and VEGF might play a role in the onset or development of superficial infantile hemangiomas.
Elevated levels of circulating (pro)renin were observed in pre-eclampsia patients
The results suggest that variants in the enhancer region of the human renin gene have an effect on the expression levels of renin in renal tissue; this observation is in good accordance with the results of the transcriptional assay.
Aliskiren prevents renal disease progression by suppressing both angiotensin I and II in human renin angiotensinogen (show AGT Antibodies) transgenic mice with high salt loading.
Demonstrate that there are strong interactions between prorenin, ATP6AP2 (show ATP6AP2 Antibodies), and TGFB1 (show TGFB1 Antibodies) and that this system has a greater capacity in female amnion to stimulate profibrotic pathways, thus maintaining the integrity of the fetal membranes.
the aldosterone-renin ratio may have role in total and cancer death in Japanese individuals
We conclude that heterozygous substitutions at AGT (show AGXT Antibodies) and REN loci correlate significantly with end-stage renal disease in a north Indian population
Salt supplementation blunts the telmisartan induced increase in plasma renin activity in patients with type 2 diabetes.
our data suggest that the renin polymorphism plays an important role in the risk of developing coronary artery disease with the highest risk for C allele, but do not support its role as a risk factor for developing restenosis after coronary stenting
This study showed no involvement of A/G renin polymorphisms in the pathogenesis of heart failure.
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.
, BTB/POZ domain-containing protein KCTD11
, retinoic acid, EGF, and NGF upregulated
, renin 1 structural
, angiotensin-forming enzyme
, renin precursor, renal