Browse our Cathepsin L1 (CTSL1) ELISA Kits

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Cathepsin L1 ELISA Kits (CTSL1)
On www.antibodies-online.com are 50 Cathepsin L1 (CTSL1) ELISA Kits from 14 different suppliers available. Additionally we are shipping Cathepsin L1 Antibodies (178) and Cathepsin L1 Proteins (42) and many more products for this protein. A total of 283 Cathepsin L1 products are currently listed.
Synonyms:
1190035F06Rik, CATHL, CatL, cpl-1, Ctsl, Ctsl1, CTSL2, fs, MEP, MGC80629, MGC107932, nkt, si:dkey-121a11.6
list all ELISA KIts Gene Name GeneID UniProt
CTSL1 1514 P07711
CTSL1 13039 P06797
CTSL1 25697 P07154

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Top referenced Cathepsin L1 ELISA Kits

  1. ABIN411884 : Yamada, Ishimaru, Arakaki, Katunuma, Hayashi: Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8(+) T cell activity. in PLoS ONE 2010 (PubMed)
    Show all 3 references for 411884

  2. Human Cathepsin L1 ELISA Kit for Sandwich ELISA - ABIN414965 : Zhang, Wang, Huang, Li, Zhu, Luo, Shi, Li: Plasma cathepsin L and its related pro/antiangiogenic factors play useful roles in predicting rich coronary collaterals in patients with coronary heart disease. in The Journal of international medical research 2010 (PubMed)
    Show all 2 references for 414965

  3. Rat (Rattus) Cathepsin L1 ELISA Kit for Sandwich ELISA - ABIN416447 : Bauer, Hess, Qiu, Klenk, Renault, Wanner, Studer, Killer, Stalder, Stritt, Strasser, Farine, Kauser, Clozel, Fischli, Nayler: Identification of cathepsin L as a potential sex-specific biomarker for renal damage. in Hypertension 2011 (PubMed)

More ELISA Kits for Cathepsin L1 Interaction Partners

Xenopus laevis Cathepsin L1 (CTSL1) interaction partners

  1. These results suggest that an antipain-sensitive protease or cathepsin L (or a related protease) is a candidate for pp25 degradation.

Human Cathepsin L1 (CTSL1) interaction partners

  1. Collectively, these data indicate that CTSL is an important contributor to tumor angiogenesis and that the CTSL inhibition may have therapeutic utility in the treatment of breast cancer patients.

  2. Therefore, we show for the first time that the nuclear localization of Cat L (show TRPV6 ELISA Kits) and its substrate Cux1can be positively regulated by Snail (show SNAI1 ELISA Kits) NLS (show ALDH1A2 ELISA Kits) and importin (show KPNA4 ELISA Kits) beta1, suggesting that Snail (show SNAI1 ELISA Kits), Cat L (show TRPV6 ELISA Kits) and Cux1 (show CUX1 ELISA Kits) all utilize importin (show KPNA4 ELISA Kits) beta1 for nuclear import.

  3. Data suggest substrate specificity of CTSL includes SNCA (show SNCA ELISA Kits); CTSL truncates SNCA (show SNCA ELISA Kits) first at C-terminus before attacking internal beta-sheet-rich region between residues 30 and 100; three of four proteolysis sites contain glycine residues likely involved in beta-turn, where proteolysis leads to solvent exposure of internal residues and further proteolysis of amyloid. (CTSL = cathepsin L; SNCA (show SNCA ELISA Kits) = alpha-synuclein (show SNCA ELISA Kits))

  4. Cathepsin L knockdown induced by RNA interference significantly promoted curcumin-induced cytotoxicity, apoptosis, and cell cycle arrest. The knockdown also inhibited the migration and invasion of glioma cells. Cathepsin L may be a new target to enhance the efficacy of curcumin against cancers.

  5. a positive feedback loop between Snail (show SNAI1 ELISA Kits)-nuclear Cat L (show TRPV6 ELISA Kits)-CUX1 (show CUX1 ELISA Kits) drives epithelial mesenchymal transition, is reprted.

  6. CtsB (show CTSB ELISA Kits)/L as major regulators of lysosomal function and demonstrate that CtsB (show CTSB ELISA Kits)/L may play an important role in intracellular cholesterol trafficking and in degradation of the key AD proteins

  7. Kidney tubule/glomerulus cathepsin L expression did not change in cyclosporine A-treated nephrotic syndrome.

  8. interactions of human family 1 & 2 cystatins with cathepsin L1

  9. cathepsin L and cathepsin B (show CTSB ELISA Kits) as the lysosomal cysteine proteases that activate the PEDV spike.

  10. the crystal structure determined at 1.4 A revealed that the cathepsin L molecule is cleaved, with the cleaved region trapped in the active site cleft of the neighboring molecule.

Mouse (Murine) Cathepsin L1 (CTSL1) interaction partners

  1. Exposure of J774A.1 cells to HOCl or HOSCN resulted in a significant decrease in the activity of the Cys (show DNAJC5 ELISA Kits)-dependent cathepsins B and L, but not the Asp (show C3 ELISA Kits)-dependent cathepsin D (show CTSD ELISA Kits).

  2. findings suggest that single chain-cathepsin L is biologically active in promoting Th17 generation and is counter-regulated by serpinB1 (show SERPINB1 ELISA Kits) and secondarily by asparagine endopeptidase.

  3. CTSL plays an important role in the MHC class II-mediated peptide presentation in thymic epithelial cells, acting both in the invariant chain degradation and in the generation of MHC class II-bound peptide ligands presented by cortical thymic epithelial cells. Consequently, CTSL plays an important role in the positive selection of CD4 (show CD4 ELISA Kits)+ T cell in thymus.

  4. genetic blockade of cathepsin L activity is inferred to retard Myc (show MYC ELISA Kits)-driven tumor growth, encouraging the potential utility of pharmacological inhibitors of cysteine cathepsins in treating late stage tumors.

  5. Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L, cathepsin C (show CTSC ELISA Kits), and TINAGL1 (show TINAGL1 ELISA Kits) in placenta.

  6. CtsB (show CTSB ELISA Kits) and CtsL are essential in alpha-syn lysosomal degradation

  7. The phenotypes of cathepsin L deficiency can be fully assigned to lack of canonically targeted cathepsin L, while the biogenesis and functionality of nucleo-cytosolic cathepsin L remain elusive.

  8. in vivo functional evidence for overexpressed CTSL as a promoter of lung metastasis, whereas high CTSL levels are maintained during tumor progression due to stress-resistant mRNA translation.

  9. cathepsin L has a protective role in mouse skin carcinogenesis

  10. Cathepsin L is involved in nociception in mice, whereas peripheral autophagy and cathepsin L contribute, at least in part, to the antinociceptive effect of dimethoxybenzylidene in mice.

Pig (Porcine) Cathepsin L1 (CTSL1) interaction partners

  1. Endosomal acidification and cathepsin L (show CTSL ELISA Kits) activity is required for porcine enteric calicivirus replication.

  2. CTSL1 is expressed by endometrial epithelia, placental areolae, and neonatal intestine, and it may function in the transport of macromolecules across these epithelia.

  3. These results, together with those previously reported for other genes of this family, suggest that cathepsin genes play a role in defining economically important traits in pigs.

Cow (Bovine) Cathepsin L1 (CTSL1) interaction partners

  1. The cathepsin L (show CTSL ELISA Kits) deserves further evaluation as therapeutic targets to develop disease modifying drugs to treat Alzheimer's disease.

  2. Cathepsin L (show CTSL ELISA Kits) has an previously uncharacterized biological role in the production of [Met]enkephalin, an endogenous peptide neurotransmitter

  3. Secretory vesicle function of cathepsin L (show CTSL ELISA Kits) for biosynthesis of active enkephalin opioid peptide contrasts with its function in lysosomes for protein degradation.

Cathepsin L1 (CTSL1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with Cathepsin L1 (CTSL1)

  • cathepsin K, like (ctskl) Elisa Kit
  • cathepsin L1 (ctsl1) Elisa Kit
  • cathepsin L1 (CTSL1) Elisa Kit
  • Cathepsin L1 (catl1) Elisa Kit
  • cathepsin L1 (Tsp_11596) Elisa Kit
  • cathepsin L (CTSL) Elisa Kit
  • cathepsin L (Ctsl) Elisa Kit
  • cathepsin L family member 3 (CTSL3) Elisa Kit
  • cathepsin L1 (Ctsl1) Elisa Kit
  • cathepsin L2 (CTSL2) Elisa Kit
  • 1190035F06Rik Elisa Kit
  • CATHL Elisa Kit
  • CatL Elisa Kit
  • cpl-1 Elisa Kit
  • Ctsl Elisa Kit
  • Ctsl1 Elisa Kit
  • CTSL2 Elisa Kit
  • fs Elisa Kit
  • MEP Elisa Kit
  • MGC80629 Elisa Kit
  • MGC107932 Elisa Kit
  • nkt Elisa Kit
  • si:dkey-121a11.6 Elisa Kit

Protein level used designations for Cathepsin L1 (CTSL1) ELISA Kits

cathepsin L1 , cathepsin L , Cathepsin L1 , cathepsin L1-like , major excreted protein , Cat L , furless , nackt , p39 cysteine proteinase , CP-2 , MEP , cyclic protein 2 , cathepsin L2 preproprotein

GENE ID SPECIES
567046 Danio rerio
444163 Xenopus laevis
548464 Xenopus (Silurana) tropicalis
737449 Pan troglodytes
100286607 Salmo salar
100412536 Callithrix jacchus
10912974 Trichinella spiralis
100604414 Nomascus leucogenys
1514 Homo sapiens
13039 Mus musculus
484140 Canis lupus familiaris
25697 Rattus norvegicus
396926 Sus scrofa
515200 Bos taurus
100008830 Oryctolagus cuniculus
101113725 Ovis aries
281108 Bos taurus
427466 Gallus gallus
100684364 Canis lupus familiaris
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