Browse our anti-DDX58 (DDX58) Antibodies

Full name:
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 Antibodies (DDX58)
On are 174 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) Antibodies from 27 different suppliers available. Additionally we are shipping DDX58 Proteins (12) and DDX58 Kits (9) and many more products for this protein. A total of 201 DDX58 products are currently listed.
6430573D20Rik, C330021E21, RHIV-1, RIG-1, RIG-I, RIGI, RLR-1
list all antibodies Gene Name GeneID UniProt
DDX58 23586 O95786
DDX58 230073 Q6Q899
DDX58 297989  

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anti-Human DDX58 Antibodies:

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Top referenced anti-DDX58 Antibodies

  1. Human Polyclonal DDX58 Primary Antibody for WB - ABIN388602 : Bao, Liu, Shan, Li, Garofalo, Casola: Human metapneumovirus glycoprotein G inhibits innate immune responses. in PLoS pathogens 2008 (PubMed)
    Show all 9 references for 388602

  2. Human Polyclonal DDX58 Primary Antibody for EIA, WB - ABIN357193 : Li, Chen, Kato, Gale, Lemon: Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for 357193

  3. Human Polyclonal DDX58 Primary Antibody for EIA, WB - ABIN357195 : Breiman, Grandvaux, Lin, Ottone, Akira, Yoneyama, Fujita, Hiscott, Meurs: Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon. in Journal of virology 2005 (PubMed)
    Show all 5 references for 357195

  4. Human Monoclonal DDX58 Primary Antibody for IP, IHC - ABIN1169336 : Gack, Nistal-Villán, Inn, García-Sastre, Jung: Phosphorylation-mediated negative regulation of RIG-I antiviral activity. in Journal of virology 2010 (PubMed)
    Show all 4 references for 1169336

  5. Human Polyclonal DDX58 Primary Antibody for ELISA, IHC - ABIN4350536 : Zhu, Duan, Wang, Cao, Liu: TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages. in Experimental cell research 2016 (PubMed)

  6. Human Polyclonal DDX58 Primary Antibody for IHC (p), WB - ABIN4350540 : Seki, Yoshizumi, Tanaka, Ryo, Ishioka, Tsukagoshi, Kozawa, Okayama, Okabe-Kado, Goya, Kimura: Cytokine profiles, signalling pathways and effects of fluticasone propionate in respiratory syncytial virus-infected human foetal lung fibroblasts. in Cell biology international 2014 (PubMed)

  7. Human Polyclonal DDX58 Primary Antibody for EIA, IHC (p) - ABIN500606 : Akira, Uematsu, Takeuchi: Pathogen recognition and innate immunity. in Cell 2006 (PubMed)

  8. Human Monoclonal DDX58 Primary Antibody for IHC, IHC (p) - ABIN4350538 : Pei, Deng, Ye, Wang, Gou, Liu, Zhao, Liao, Yi, Chen: Absence of autophagy promotes apoptosis by modulating the ROS-dependent RLR signaling pathway in classical swine fever virus-infected cells. in Autophagy 2016 (PubMed)

  9. Horse (Equine) Polyclonal DDX58 Primary Antibody for WB - ABIN2775222 : Miyazaki, Kanto, Inoue, Itose, Miyatake, Sakakibara, Yakushijin, Kakita, Hiramatsu, Takehara, Kasahara, Hayashi: Impaired cytokine response in myeloid dendritic cells in chronic hepatitis C virus infection regardless of enhanced expression of Toll-like receptors and retinoic acid inducible gene-I. in Journal of medical virology 2008 (PubMed)

More Antibodies against DDX58 Interaction Partners

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) interaction partners

  1. Taken together, the present study reveals that T80 phosphorylation of influenza A virus NS1 reduced virus replication through controlling RIG-I-mediated interferon production and viral ribonucleoprotein activity.

  2. results suggest that RNAs containing modified nucleotides interrupt signaling at early steps of the RIG-I-like innate immune activation pathway

  3. The authors found that in Sendai virus C protein (show HNRNPC Antibodies) deletion mutant-infected cells, Sendai virus defective interfering RNA also functioned as an exclusive RIG-I ligand.

  4. ArfGAP domain-containing protein 2 (ADAP2 (show ADAP2 Antibodies)) is identified as a key novel scaffolding protein that integrates different modules of the RIG-I pathway, located at distinct subcellular locations, and mediates cellular antiviral type I interferon (show IFNA Antibodies) production.

  5. the bending structure of the panhandle RNA negates the requirement of a 5'-PPP moiety for RIG-I activation.

  6. RIG-I-like receptor-induced IRF3 (show IRF3 Antibodies) mediated pathway of apoptosis (RIPA): a new antiviral pathway

  7. These data validate BRD4 (show BRD4 Antibodies) as a major effector of respiratory syncytial virus-induced inflammation and disease. BRD4 (show BRD4 Antibodies) is required for coupling NF-kappaB (show NFKB1 Antibodies) to expression of inflammatory genes and the IRF (show TRIM63 Antibodies)-RIG-I autoamplification pathway and independently facilitates antiviral interferon (show IFNA Antibodies)-stimulated gene expression.

  8. The severe acute respiratory syndrome coronavirus N protein was found to bind to the SPRY domain of the tripartite motif protein 25 (TRIM25 (show TRIM25 Antibodies)) E3 ubiquitin ligase (show MUL1 Antibodies), thereby interfering with the association between TRIM25 (show TRIM25 Antibodies) and retinoic acid-inducible gene I (RIG-I) and inhibiting TRIM25 (show TRIM25 Antibodies)-mediated RIG-I ubiquitination and activation.

  9. The regulation of STING via RIG-I-mediated innate immune sensing.

  10. These results suggest that inhibition of RIG-I-mediated type I interferon (show IFNA Antibodies) responses by Enterovirus 71 may contribute to the pathogenesis of viral infection.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) interaction partners

  1. Data suggest that activation of either RIG-I/MAVS (show MAVS Antibodies) or STING pathways during acute intestinal tissue injury in mice resulted in IFN-I signaling that maintained gut (show GUSB Antibodies) epithelial barrier integrity and reduced GVHD severity.

  2. RIG-I subsequently localized to antiviral stress granules induced after viral replication complexes formation

  3. identifies DDX58 and MTHFSD as two TDP-43 (show TARDBP Antibodies) targets that are misregulated in amyotrophic lateral sclerosis. 1

  4. Data show that preconditioning with poly(I:C) alters toll (show TLR4 Antibodies)-like receptors (TLR) and RIG-I-like receptors (RLRs) responses in opposite directions.

  5. Cytosolic LMW FGF2 (show FGF2 Antibodies) functions as a negative regulator in RIG-I-mediated antiviral signaling.

  6. results indicate that Lyn (show LYN Antibodies) plays a positive regulatory role in RIG-I-mediated interferon (show IFNA Antibodies) expression as a downstream component of IPS-1 (show ISYNA1 Antibodies)

  7. In lung epithelial cells, retinoic acid-inducible gene-1 (show RARRES3 Antibodies) (RIG-I) was identified as the major RIG-I-like receptor required for RSV-induced protease expression via MAVS (show MAVS Antibodies).

  8. findings suggest that RIG-I directs a typical IFN-dependent antiviral response against an RNA virus capable of suppressing the RNAi response

  9. The results describe a novel, interactive relationship between RIG-I downstream signalling molecules resulting in efficient anti-viral immunity.

  10. senses hepatitis B virus RNA, and counteracts HBV polymerase

Pig (Porcine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58) interaction partners

  1. Viral RNA polymerase components PB2, PB1, and PA directly target RIG-I.

  2. These data indicate that classical swine fever virus can be recognized by both RIG-I and MDA5 (show IFIH1 Antibodies) to initiate the RIG-I signaling pathway to trigger innate defenses against infection.

  3. DDX58 had two nonsynonymous SNPs in the helicase (show DNA2 Antibodies) domain.

DDX58 Antigen Profile

Antigen Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.

Alternative names and synonyms associated with DDX58

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (DDX58) antibody
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Ddx58) antibody
  • 6430573D20Rik antibody
  • C330021E21 antibody
  • RHIV-1 antibody
  • RIG-1 antibody
  • RIG-I antibody
  • RIGI antibody
  • RLR-1 antibody

Protein level used designations for DDX58

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I , probable ATP-dependent RNA helicase DDX58 , putative ATP-dependent RNA helicase DDX58 , retinoic acid-inducible protein I , DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 , probable ATP-dependent RNA helicase DDX58-like , DEAD box protein 58 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide , RIG-1 , RIG-I-like receptor 1 , RNA helicase RIG-I , retinoic acid inducible gene I , retinoic acid-inducible gene 1 protein , retinoic acid-inducible gene I protein , DEAD-box protein 58 , DEAD/H box polypeptide RIG-I , retinoic acid-inducible gene-I , RNA helicase induced by virus

465035 Pan troglodytes
704638 Macaca mulatta
100067920 Equus caballus
100347707 Oryctolagus cuniculus
100408692 Callithrix jacchus
100443290 Pongo abelii
23586 Homo sapiens
230073 Mus musculus
297989 Rattus norvegicus
100686785 Canis lupus familiaris
396723 Sus scrofa
504760 Bos taurus
101107257 Ovis aries
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