Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human DDX58 Antibodies:
anti-Mouse (Murine) DDX58 Antibodies:
anti-Rat (Rattus) DDX58 Antibodies:
Go to our pre-filtered search.
Human Polyclonal DDX58 Primary Antibody for WB - ABIN388602
Bao, Liu, Shan, Li, Garofalo, Casola: Human metapneumovirus glycoprotein G inhibits innate immune responses. in PLoS pathogens 2008
Show all 9 Pubmed References
Human Polyclonal DDX58 Primary Antibody for IHC - ABIN965986
Imaizumi, Aratani, Nakajima, Carlson, Matsumiya, Tanji, Ookawa, Yoshida, Tsuchida, McIntyre, Prescott, Zimmerman, Satoh: Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2. in Biochemical and biophysical research communications 2002
Show all 8 Pubmed References
Human Polyclonal DDX58 Primary Antibody for IHC - ABIN965987
Cui, Imaizumi, Yoshida, Borden, Satoh: Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates the expression of interferon-gamma stimulated gene 15 in MCF-7 cells. in Biochemistry and cell biology = Biochimie et biologie cellulaire 2004
Show all 6 Pubmed References
Human Polyclonal DDX58 Primary Antibody for IHC - ABIN965985
Yoneyama, Kikuchi, Natsukawa, Shinobu, Imaizumi, Miyagishi, Taira, Akira, Fujita: The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. in Nature immunology 2004
Show all 6 Pubmed References
Human Monoclonal DDX58 Primary Antibody for IP, IHC - ABIN1169336
Gack, Nistal-Villán, Inn, García-Sastre, Jung: Phosphorylation-mediated negative regulation of RIG-I antiviral activity. in Journal of virology 2010
Show all 4 Pubmed References
Human Polyclonal DDX58 Primary Antibody for IHC (p), WB - ABIN2476365
Chapuis, Knobel, Loup, von Niederhäusern: [Isolated renal angiomyolipoma]. in Helvetica chirurgica acta 1976
Show all 4 Pubmed References
Human Polyclonal DDX58 Primary Antibody for IHC, ELISA - ABIN1003083
Alexopoulou, Holt, Medzhitov, Flavell: Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. in Nature 2001
Show all 4 Pubmed References
Human Monoclonal DDX58 Primary Antibody for IHC, IHC (p) - ABIN4350538
Pei, Deng, Ye, Wang, Gou, Liu, Zhao, Liao, Yi, Chen: Absence of autophagy promotes apoptosis by modulating the ROS-dependent RLR signaling pathway in classical swine fever virus-infected cells. in Autophagy 2016
Human Polyclonal DDX58 Primary Antibody for IHC (p), WB - ABIN4350540
Seki, Yoshizumi, Tanaka, Ryo, Ishioka, Tsukagoshi, Kozawa, Okayama, Okabe-Kado, Goya, Kimura: Cytokine profiles, signalling pathways and effects of fluticasone propionate in respiratory syncytial virus-infected human foetal lung fibroblasts. in Cell biology international 2014
Human Polyclonal DDX58 Primary Antibody for ELISA, IHC - ABIN4350536
Zhu, Duan, Wang, Cao, Liu: TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages. in Experimental cell research 2016
This study evaluation the roles of SOCS1 (show SOCS1 Antibodies), the regulator of TLR9 (show TLR9 Antibodies), RIG-I, and CD152 (show CTLA4 Antibodies) in patients with liver fibrosis/cirrhosis; the use of polymorphisms as markers for genetic risk is reported.
study documents that recombinant measles virus produce defective interfering genomes that have high immunostimulatory properties via their binding to RIG-I and LGP2 (show DHX58 Antibodies) proteins, both of which are cytosolic nonself RNA sensors of innate immunity.
findings define the WHIP (show WRNIP1 Antibodies)-TRIM14 (show TRIM14 Antibodies)-PPP6C (show PPP6C Antibodies) mitochondrial signalosome required for RIG-I-mediated innate antiviral immunity.
both IL-6 (show IL6 Antibodies) and RIG-I are downstream molecules of STING along the DNA sensor pathway.
These data suggest that prior exposure to IFN-gamma (show IFNG Antibodies) may leave an epigenetic mark on the chromatin that enhances airway cells' ability to resist infection, possibly via epigenetic upregulation of RIG-I.
findings show that RIG-I and MDA5 (show IFIH1 Antibodies) triggering by dengue virus leads to TH1 (show TH1L Antibodies) polarization, which is characterized by high levels of IFN-gamma (show IFNG Antibodies); identified RIG-I and MDA5 (show IFIH1 Antibodies) as critical players in innate and adaptive immune responses against Dengue virus
Results identified a negative-feedback mechanism that targets RIG-I activity mediated by DAPK1 (show DAPK1 Antibodies). RIG-I-mediated antiviral signaling activates DAPK1 (show DAPK1 Antibodies) kinase activity and DAPK1 (show DAPK1 Antibodies) inactivates RIG-I RNA sensing by direct phosphorylation of RIG-I.
Mechanistically, West Nile virus NS1 (show PTPN11 Antibodies) targets RIG-I and melanoma differentiation-associated gene 5 (MDA5 (show IFIH1 Antibodies)) by interacting with them and subsequently causing their degradation by the proteasome.
RIG-I stimulates the cellular innate immunity against hepatitis E virus infections.
dynamic sumoylation and desumoylation of MDA5 (show IFIH1 Antibodies) and RIG-I modulate efficient innate immunity to RNA virus and its timely termination.
Collectively, these results uncover an independent functional contribution of the apo (show C9orf3 Antibodies)-Rig-I/Stat3 (show STAT3 Antibodies) interaction in the maintenance of Treg/Th17 cell balance.
The RIG-I, as well as the adaptor protein mitochondrial antiviral signaling protein (show MAVS Antibodies), regulates NF-kappaB (show NFKB1 Antibodies)-mediated induction of adhesion molecules and proinflammatory cytokine expression in response to LPS (show TLR4 Antibodies).
Data suggest that activation of either RIG-I/MAVS (show MAVS Antibodies) or STING pathways during acute intestinal tissue injury in mice resulted in IFN-I signaling that maintained gut (show GUSB Antibodies) epithelial barrier integrity and reduced GVHD severity.
RIG-I subsequently localized to antiviral stress granules induced after viral replication complexes formation
identifies DDX58 and MTHFSD as two TDP-43 (show TARDBP Antibodies) targets that are misregulated in amyotrophic lateral sclerosis. 1
Data show that preconditioning with poly(I:C) alters toll (show TLR4 Antibodies)-like receptors (TLR) and RIG-I-like receptors (RLRs) responses in opposite directions.
Cytosolic LMW FGF2 (show FGF2 Antibodies) functions as a negative regulator in RIG-I-mediated antiviral signaling.
results indicate that Lyn (show LYN Antibodies) plays a positive regulatory role in RIG-I-mediated interferon (show IFNA Antibodies) expression as a downstream component of IPS-1 (show ISYNA1 Antibodies)
In lung epithelial cells, retinoic acid-inducible gene-1 (show RARRES3 Antibodies) (RIG-I) was identified as the major RIG-I-like receptor required for RSV-induced protease expression via MAVS (show MAVS Antibodies).
findings suggest that RIG-I directs a typical IFN-dependent antiviral response against an RNA virus capable of suppressing the RNAi response
Viral RNA polymerase components PB2, PB1, and PA directly target RIG-I.
These data indicate that classical swine fever virus can be recognized by both RIG-I and MDA5 (show IFIH1 Antibodies) to initiate the RIG-I signaling pathway to trigger innate defenses against infection.
DDX58 had two nonsynonymous SNPs in the helicase (show DNA2 Antibodies) domain.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
, probable ATP-dependent RNA helicase DDX58
, putative ATP-dependent RNA helicase DDX58
, retinoic acid-inducible protein I
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
, probable ATP-dependent RNA helicase DDX58-like
, DEAD box protein 58
, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
, RIG-I-like receptor 1
, RNA helicase RIG-I
, retinoic acid inducible gene I
, retinoic acid-inducible gene 1 protein
, retinoic acid-inducible gene I protein
, DEAD-box protein 58
, DEAD/H box polypeptide RIG-I
, retinoic acid-inducible gene-I
, RNA helicase induced by virus