Browse our anti-NOD2 (NOD2) Antibodies

Full name:
anti-Nucleotide-Binding Oligomerization Domain Containing 2 Antibodies (NOD2)
On are 148 Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Antibodies from 21 different suppliers available. Additionally we are shipping NOD2 Kits (4) and and many more products for this protein. A total of 163 NOD2 products are currently listed.
ACUG, BLAU, Card15, CD, CLR16.3, F830032C23Rik, IBD1, Nlrc2, NOD2B, PSORAS1
list all antibodies Gene Name GeneID UniProt
NOD2 64127 Q9HC29
NOD2 257632  
NOD2 291912  

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Top referenced anti-NOD2 Antibodies

  1. Human Monoclonal NOD2 Primary Antibody for FACS, ICC - ABIN151959 : McDonald, Chen, Ollendorff, Ogura, Marchetto, Lécine, Borg, Nuñez: A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. in The Journal of biological chemistry 2005 (PubMed)
    Show all 13 references for 151959

  2. Human Polyclonal NOD2 Primary Antibody for ICC, IF - ABIN153051 : Till, Rosenstiel, Bräutigam, Sina, Jacobs, Oberg, Seegert, Chakraborty, Schreiber: A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion. in Journal of cell science 2008 (PubMed)
    Show all 5 references for 153051

  3. Human Polyclonal NOD2 Primary Antibody for IF, WB - ABIN318706 : Inohara, Nuñez: NODs: intracellular proteins involved in inflammation and apoptosis. in Nature reviews. Immunology 2003 (PubMed)
    Show all 3 references for 318706

  4. Human Polyclonal NOD2 Primary Antibody for ELISA, ICC - ABIN4340247 : Rahman, Midtling, Svingen, Xiong, Bell, Tung, Smyrk, Egan, Faubion: The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

  5. Human Monoclonal NOD2 Primary Antibody for ICC, IF - ABIN1721812 : Cooney, Baker, Brain, Danis, Pichulik, Allan, Ferguson, Campbell, Jewell, Simmons: NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. in Nature medicine 2010 (PubMed)

  6. Human Monoclonal NOD2 Primary Antibody for FACS, ICC - ABIN4340264 : Subramanian, Bergman, Henriques-Normark: Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils. in Journal of innate immunity 2017 (PubMed)

  7. Human Polyclonal NOD2 Primary Antibody for ELISA, WB - ABIN185703 : Keshav: Paneth cells: leukocyte-like mediators of innate immunity in the intestine. in Journal of leukocyte biology 2006 (PubMed)

More Antibodies against NOD2 Interaction Partners

Human Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. Performed genetic analysis in patients with Crohn's disease (CD) to determine effect of NOD2/CARD15 polymorphisms on treatment response to adalimumab and infliximab.

  2. The study of the correlation between genotype and phenotypic expression showed that CARD15 mutation is associated with ileocecal Crohn's disease, with fistulizing and stenosing behavior in Crohn's disease as well as with severe evolution

  3. Ligand-driven triggering of TLR-3 (show TLR3 Antibodies), -4, NOD2, and DC-SIGN (show CD209 Antibodies), despite reducing viral replication, markedly increased the capacity of infected dendritic cells to stimulate HIV-specific cytotoxic T-cells.

  4. This work suggests that Crohn's Disease-associated Nod2 variants could be stabilized in vivo with a molecular chaperone (show HSP90AA1 Antibodies).

  5. From the results, the authors conclude that SNPs at the NOD2 and IL6 (show IL6 Antibodies) genes are associated with leprosy reactions as an outcome.

  6. NOD2 rs3135500 and IL12B (show IL12B Antibodies) rs1368439 SNPs were not genetic risk factors for colorectal cancer in the studied Iranian population.

  7. Variants of NOD2/CARD15 and TLR4 (show TLR4 Antibodies) do not confer susceptibility to inflammatory bowel disease, but appear to determine Crohn's disease phenotypes in this southeastern Brazilian population.

  8. IFNgamma positively affects NOD2-mediated signaling in human conventional dendritic cells, in a manner considerably dependent on XIAP (show XIAP Antibodies) and partially dependent on mTOR (show FRAP1 Antibodies).

  9. The role of the NOD2 risk variants in bacterial translocation and spontaneous bacterial peritonitis is reported.

  10. This study provides the evidence of NOD2/TLR2 (show TLR2 Antibodies)-mediated exacerbation of Atopic dermatitis through activation of innate immune cells.

Mouse (Murine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. this study shows that the effect of the gut (show GUSB Antibodies) microbiota on bone is dependent on NOD1 (show NOD1 Antibodies) and NOD2 signaling

  2. this study shows that microbial sensing by Nod2 is an important mechanism to regulate small intestinal mucosal damage following acute T cell activation

  3. results demonstrate that the recognition of bacterial products by NOD2 inside the PLNs contributes to T1D development, establishing a new putative target for intervention during the early stages of the disease.

  4. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies)-FOXO1 (show FOXO1 Antibodies) signaling and suppressing the activation of TLR4 (show TLR4 Antibodies) and/or NOD2 signaling pathways.

  5. this study shows that innate immunity activation by muramyl peptides is mediated via an interaction between YB1 (show YBX1 Antibodies) and NOD2

  6. this study shows that NOD2 is important for osteoclast differentiation and inflammatory bone resorption in vivo and also for the macrophage response to Gram-negative bacteria

  7. this study reveals that LRRK2 (show LRRK2 Antibodies) is a new positive regulator of Rip2 (show ARHGDIG Antibodies) and promotes inflammatory cytokine induction through the Nod1 (show NOD1 Antibodies)/2-Rip2 (show ARHGDIG Antibodies) pathway.

  8. This study signifies that NOD-2 and TLR-4 (show TLR4 Antibodies) exhibit synergism in invigorating the activity of dendritic cells.

  9. Deletion of the bacterial peptidoglycan sensor NOD2 had relatively minor effects on immune responses.

  10. Sertoli cells have a functional NALP3 (show NLRP3 Antibodies) inflammasome that modulates NOD1 (show NOD1 Antibodies) and pro-IL-1beta (show IL1B Antibodies) expression, while NOD2 inversely promoted IL-1beta (show IL1B Antibodies) expression.

Cow (Bovine) Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) interaction partners

  1. Data indicate six single-nucleotide polymorphisms (SNPs) in the caspase recruitment domain 15 protein (CARD15) gene associated with susceptibility to bovine tuberculosis (BTB) in Chinese Holstein cows.

  2. Data indicate that the Nod2 signaling adaptor protein (NOD2) G-->A at position 1594 bp plays a critical role in increasing 305-day milk yields.

  3. Genetic variation and putative regulatory regions in bovine CARD15.

  4. A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype.

NOD2 Antigen Profile

Antigen Summary

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Alternative names and synonyms associated with NOD2

  • caspase recruitment domain 15 protein (TTHERM_01951320) antibody
  • nucleotide-binding oligomerization domain containing 2 (NOD2) antibody
  • nucleotide-binding oligomerization domain containing 2 (Nod2) antibody
  • ACUG antibody
  • BLAU antibody
  • Card15 antibody
  • CD antibody
  • CLR16.3 antibody
  • F830032C23Rik antibody
  • IBD1 antibody
  • Nlrc2 antibody
  • NOD2B antibody
  • PSORAS1 antibody

Protein level used designations for NOD2

caspase recruitment domain 15 protein , NLR family, CARD domain containing 2 , NOD-like receptor C2 , caspase recruitment domain family, member 15 , caspase recruitment domain protein 15 , caspase recruitment domain-containing protein 15 , inflammatory bowel disease protein 1 , nucleotide-binding oligomerization domain 2 , nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2 , nucleotide-binding oligomerization domain-containing protein 2

7828465 Tetrahymena thermophila
64127 Homo sapiens
257632 Mus musculus
291912 Rattus norvegicus
444867 Bos taurus
454083 Pan troglodytes
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