Apotosis Activator 2

Details for Product No. ABIN924978, Supplier: Log in to see
Application
Apoptosis Induction (AI), Cell Culture (CC)
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Purity > 98 % by NMR analysis
Chemical Name 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione
Formula C15H9NO2Cl2
Solubility Soluble in DMSO or 100% ethanol
Molecular Weight 306.1 g/mol
Comment

Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome and triggering caspase-9 activation resulting in activated caspase-3. Shows a stronger selectivity for cancer cells than for normal cell lines. Acts in a similar fashion as apoptosis inducer alpha- (trichloromethyl)-4-pyridineethanol (PETCM).

Restrictions For Research Use only
Format Solid
Storage 4 °C