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Browse our alpha 1b Adrenergic Receptor Proteins (ADRA1B)

Full name:
Adrenergic, alpha-1B-, Receptor Proteins (ADRA1B)
On www.antibodies-online.com are 4 Adrenergic, alpha-1B-, Receptor (ADRA1B) Proteins from 1 different suppliers available. Additionally we are shipping alpha 1b Adrenergic Receptor Antibodies (122) and alpha 1b Adrenergic Receptor Kits (9) and many more products for this protein. A total of 143 alpha 1b Adrenergic Receptor products are currently listed.
Synonyms:
ADRA1, ALPHA1BAR, LOC100136712, RDC5, [a]1b
list all proteins Gene Name GeneID UniProt
ADRA1B 11548  
ADRA1B 147 P35368
Rat ADRA1B ADRA1B 24173  

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alpha 1b Adrenergic Receptor Proteins (ADRA1B) by Origin

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More Proteins for alpha 1b Adrenergic Receptor Interaction Partners

Mouse (Murine) Adrenergic, alpha-1B-, Receptor (ADRA1B) interaction partners

  1. eIF3f (show EIF3F Proteins)/alpha adrenergic receptor interaction

  2. The adra1b mediates adrenergic vasoconstriction in mouse retinal arterioles with damaged endothelium

  3. in mouse ureters: the mRNA for the alpha1A-adrenoceptor was more prevalent than those for the alpha1B- and alpha1D-adrenoceptors

  4. Overexpression of the alpha(1B (show CACNA1B Proteins))-AR in mice can cause a synucleinopathy with excessive tyrosine nitration but decreased phoshorylation similar to parkinsonian syndromes

  5. alpha(1)-ARs (show SLURP1 Proteins) in male mice are required for the physiological hypertrophy of normal postnatal cardiac development and for an adaptive response to cardiac stress

  6. alpha(1A)- and alpha(1B (show CACNA1B Proteins))-adrenoceptors have roles in myocardial contractions

  7. ADRA1b has a role in regulating glucose homeostasis in mice

  8. These results demonstrate a critical role for the alpha(1B (show CACNA1B Proteins))AR in baroreceptor-mediated adrenergic signaling at the vascular neuroeffector junction. Moreover, alpha(1B (show CACNA1B Proteins))ARs (show SLURP1 Proteins) modulate inotropic responses to baroreceptor activation.

  9. alpha1B-ARs (show SLURP1 Proteins) are the major alpha1-AR subtype expressed in DU145, PC3 (show BTG2 Proteins), and all TRAMP (show DPT Proteins) cell lines, but most of the receptor is localized in intracellular compartments in a nonfunctional state, which can be rescued upon prolonged incubation with any ligand.

  10. These results suggest that lack of both alpha(1A)- and alpha(1B (show CACNA1B Proteins))-ARs (show SLURP1 Proteins) could be necessary to inhibit neointimal formation in the mouse femoral artery.

Human Adrenergic, alpha-1B-, Receptor (ADRA1B) interaction partners

  1. eIF3f (show EIF3F Proteins)/alpha adrenergic receptor interaction

  2. alpha1A-adrenergic receptors are stably expressed and stimulate cell migration and TGF-beta1 (show TGFB1 Proteins), IGF-1 (show IGF1 Proteins), hyaluronan and PIP (show PIP Proteins) production in human skin fibroblasts.

  3. heteromeric receptor complexes between alpha1A-AR and CXCR4 (show CXCR4 Proteins) and between alpha1B-AR and CXCR4 (show CXCR4 Proteins) are constitutively expressed in rat and human vascular smooth muscle cells; the quaternary structure of the receptor complex is important for signaling and contraction

  4. alpha1B-AR signals through calcium, ERK1/2 and p38 (show CRK Proteins) only when located in the membrane and the signals disappear by membrane disruption.

  5. A rare ADRA1B haplotype composed of six single nucleotide polymorphism(SNP)s is associated with attention deficit hyperactivity disorder (ADHD).

  6. Noradrenaline facilitated cell proliferation by regulation of potassium currents in human osteoblasts via G(i/o) -protein-coupled alpha(1B (show CACNA1B Proteins)) -adrenoceptors, not via coupling to Gq-proteins

  7. Data show that sphingosine 1-phosphate can induce alpha1B-adrenergic receptor internalization and that its autocrine/paracrine generation is relevant for internalization induced by IGF-I (show IGF1 Proteins).

  8. A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation.

  9. These results are the first to demonstrate alpha1-ARs (show SLURP1 Proteins) on human coronary ECs and indicate that the alpha1B subtype is predominant.

  10. Data show thah activation of alpha(1)A- or alpha(1)B-adrenergic receptors inhibits serum-promoted cell proliferation, whereas alpha(1)D-AR activation does not show such an inhibitory effect.

alpha 1b Adrenergic Receptor (ADRA1B) Protein Profile

Protein Summary

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Alternative names and synonyms associated with alpha 1b Adrenergic Receptor (ADRA1B)

  • alpha-1B adrenoceptor (LOC100136712)
  • adrenergic, alpha-1B-, receptor (ADRA1B)
  • adrenoceptor alpha 1B (ADRA1B)
  • adrenergic receptor, alpha 1b (Adra1b)
  • adrenoceptor alpha 1B (Adra1b)
  • ADRA1 protein
  • ALPHA1BAR protein
  • LOC100136712 protein
  • RDC5 protein
  • [a]1b protein

Protein level used designations for ADRA1B

alpha-1B adrenoceptor , adrenergic, alpha-1B-, receptor , alpha-1B adrenergic receptor-like , alpha-1B adrenergic receptor , alpha-1B adrenoreceptor , alpha1B-adrenergic receptor , alpha-1B-adrenergic receptor , Adrenergic alpha 1B- receptor , adrenergic receptor, alpha 1b , alpha 1B-adrenoceptor , alpha 1B-adrenoreceptor , alpha 1b adrenoceptor

GENE ID SPECIES
100136712 Oncorhynchus mykiss
100395759 Callithrix jacchus
100482658 Ailuropoda melanoleuca
695106 Macaca mulatta
100025515 Monodelphis domestica
100543635 Meleagris gallopavo
11548 Mus musculus
407140 Bos taurus
373890 Gallus gallus
147 Homo sapiens
24173 Rattus norvegicus
403962 Canis lupus familiaris
100008731 Oryctolagus cuniculus
100519931 Sus scrofa
101843941 Mesocricetus auratus
100735480 Cavia porcellus
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