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Details for Product No. ABIN1042580

Acetyl Lysine (acLys) antibody

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Antigen
Epitope
»Alternatives acLys
Reactivity
»Alternatives Chicken, Cow (Bovine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN1042580
Quantity 0.1 mL
Price
576.05 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 6 Business Days
Immunogen Acetylated keyhole limpet hemocyanin (KLH) was used as immunogen. The cell line was screened against non acetylated KLH as a control in addition to BSA and histones
Myeloma Fusion Partners: SP2/0
Clone 7F8
Isotype IgG1
Cross-Reactivity Chicken, Cow (Bovine)
Characteristics Mouse Anti-acetyl Lysine [7F8]
Purification Protein G purified
Research Area Chromatin and Nuclear Signaling
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try 1:3000-1:10,000 for EIA
Comment

CBP and p300 are large nuclear proteins that bind to many sequencespecific factors involved in cell growth and/or differentiation, including cjun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody containing PBS 0.1% sodium azide
Preservative Sodium azide
Product cited in: Bannister, Miska: "Regulation of gene expression by transcription factor acetylation." in: Cellular and molecular life sciences : CMLS, Vol. 57, Issue 8-9, pp. 1184-92, 2000 (PubMed).

Alternatives for antigen "Acetyl Lysine", type "Antibodies"
Hosts (10), (8)
Reactivities (16), (1), (1), (1)
Applications (17), (14), (11), (5), (4), (3), (1), (1), (1), (1)
Conjugates (1), (1), (1)
Epitopes (2)
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