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Details for Product No. ABIN1042683

T Cell Receptor alpha/beta antibody

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Antigen
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunoprecipitation (IP), ELISA, Inhibition Assay (InhA), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN1042683
Quantity 0.1 mL
Price
576.05 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 5 to 6 Business Days
Immunogen 3DT-52.5 (a mouse T cell hybridoma)
Myeloma Fusion Partners: P3-x63Ag.8.653
Clone KJ1298
Isotype IgG2a
Specificity Recognises the 3DT-52.5 TcR idiotype
Characteristics Mouse Anti-TCR Alpha + TCR Beta[KJ1298]
Purification Protein G
Alternative Name T Cell Receptor alpha beta
Gene ID 21577
UniProt P01849
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline use at 5-10 µg/mL
Comment

The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody containing PBS 0.1% sodium azide
Preservative Sodium azide
Product cited in: Kappler, Kubo, Haskins et al.: "The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas." in: Cell, Vol. 34, Issue 3, pp. 727-37, 1983 (PubMed).

Alternatives for antigen "T Cell Receptor alpha/beta", type "Antibodies"
Hosts (36), (12)
Reactivities (19), (13), (9), (7)
Applications (47), (19), (15), (7), (2), (1), (1)
Conjugates (11), (8), (7), (4), (3)
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