T Cell Receptor alpha/beta antibody

Details for Product No. ABIN1042683
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Antigen
Reactivity
Mouse (Murine)
(20), (20), (12), (11)
Host
Mouse
(44), (19)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(14), (11), (9), (4), (3), (1)
Application
Immunoprecipitation (IP), ELISA, Inhibition Assay (InhA), Flow Cytometry (FACS)
(62), (28), (18), (8), (4), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN1042683
Quantity 0.1 mL
Price
576.05 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen 3DT-52.5 (a mouse T cell hybridoma)
Clone KJ1298
Isotype IgG2a
Specificity Recognises the 3DT-52.5 TcR idiotype
Characteristics Myeloma fusion partners:
P3-x63Ag.8.653
Purification Protein G
Alternative Name T Cell Receptor alpha beta
Background Synonyms:
FLJ22602 antibody,MGC117436 antibody,MGC22624 antibody,MGC23964antibody,MGC71411 antibody,T cell antigen receptor alpha polypeptide antibody,T cell antigen receptor betapolypeptide antibody,T cell antigen receptor beta polypeptide T cell receptor beta cluster antibody,T cellreceptor alpha antibody,T cell receptor alpha chain antibody,T cell receptor alpha chain C region antibody,Tcell receptor alpha chain V region CTL L17 antibody,T cell receptor alpha constant antibody,T cell receptor alphalocus antibody,T cell receptor beta chain antibody,T cell receptor beta chain V region CTL L17 antibody,T cellreceptor beta cluster antibody,T cell receptor beta locus antibody,TCRA antibody,TCRB antibody,TCRDantibody,TRA antibody,TRA@ antibody,TRAC antibody,TRB antibody,TRB@ antibody,TRDD 3 antibody,TRDD3antibody
UniProt P01849
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline use at 5-10 µg/mL
Comment

The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Product cited in: Kappler, Kubo, Haskins et al.: "The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas." in: Cell, Vol. 34, Issue 3, pp. 727-37, 1983 (PubMed).

Hosts (44), (19)
Reactivities (20), (20), (12), (11)
Applications (62), (28), (18), (8), (4), (2), (2), (2), (1), (1)
Conjugates (14), (11), (9), (4), (3), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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