NFYA antibody (N-Term)

Catalog No. ABIN104769

Product Details anti-NFYA Antibody

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFYA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: Anti-NF-Y (A) antibody was produced by repeated immunizations with a synthetic NF-Y (A subunit) peptide corresponding to a region near the of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: Anti-NF-Y antibody is suitable for western blotting and for ELISA. Researchers should determine optimal titers for applications that are not stated below.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-NFYA antibody (ABIN104769)

Falcone, Grandoni, Garibaldi, Manni, Filligoi, Piaggio, Gurtner: "Infinity: An In-Silico Tool for Genome-Wide Prediction of Specific DNA Matrices in miRNA Genomic Loci." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153658, (2016) (PubMed).

Gurtner, Fuschi, Magi, Colussi, Gaetano, Dobbelstein, Sacchi, Piaggio: "NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue." in: PLoS ONE, Vol. 3, Issue 4, pp. e2047, (2008) (PubMed).

Cecchinelli, Lavra, Rinaldo, Iacovelli, Gurtner, Gasbarri, Ulivieri, Del Prete, Trovato, Piaggio, Bartolazzi, Soddu, Sciacchitano: "Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis." in: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4746-57, (2006) (PubMed).

Yu, Zhu, Pi, Ling, Ko, Takeda, Tuan: "The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2." in: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35184-94, (2005) (PubMed).

Target Details for NFYA

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Abstract: NFYA Products

Synonyms: wu:fb16e03 antibody, ik:tdsubc_2b6 antibody, xx:tdsubc_2b6 antibody, NFYA antibody, CBF-A antibody, CBF-B antibody, HAP2 antibody, NF-YA antibody, AA407810 antibody, Cbf-b antibody, SEZ-10 antibody, SEZ10 antibody, nuclear transcription factor Y, alpha antibody, nuclear transcription factor Y subunit alpha antibody, nuclear transcription factor-Y alpha antibody, nfya antibody, NFYA antibody, Nfya antibody

Background: Anti-NF-Y antibody detects NF-Y (a subunit) protein. NF-Y is a highly conserved transcription factor that stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. NF-subunit A associates with a tight dimer composed of the NF-YB and NF-YC subunits, resulting in a trimer that binds to DNA with high specificity and affinity. Anti-NF-YA Antibody is ideal for investigators involved in Cell Signaling, Immunology, Cancer, and Signal Transduction research.
Synonyms: Nf-Y-A subunit, CAAT box DNA-binding protein subunit A, Nuclear transcription factor Y subunit A

Gene ID: 4800

UniProt: P23511

Pathways: Regulation of Lipid Metabolism by PPARalpha