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Pepsinogen C (PGC) antibody

Details for Product No. ABIN108410, Supplier: Log in to see
Antigen
  • PEPC
  • PGII
  • 2210410L06Rik
  • Upg-1
  • Upg1
  • CPGC
  • gastricsin
  • PG1
  • Pg-1
  • PGNC
  • PGC
  • Gastricsin
Reactivity
Human
99
31
22
4
3
Host
Mouse
76
40
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
14
9
6
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
68
63
25
14
11
7
5
4
3
2
1
1
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Immunogen Pepsinogen II purified from human tissue was used as an immunogen.
Clone L10CC10
Isotype IgG1
Specificity The antibody is specific to human pepsinogen II with no crossreactivity to human pepsinogen I.
Alternative Name Pepsinogen II (PGC Antibody Abstract)
Background Monoclonal Antibody to Human Gastric Biomarkers
Research Area Proteases
Pathways
Application Notes Reactivity with paraffin sections
Restrictions For Research Use only
Storage 4 °C
Background publications Yoshihara M, Sumii K, Haruma K et al.: "Correlation of ratio of serum pepsinogen I and II with prevalence of gastric cancer and adenoma in Japanese subjects." in: Am J Gastroenterol, Vol. 93, Issue 7, pp. 1090-6, 1998 (PubMed).

Aoki K, Misumi J, Kimura T et al.: "Evaluation of cutoff levels for screening of gastric cancer using serum pepsinogens and distributions of levels of serum pepsinogen I, II and of PG I/PG II ratios in a gastric cancer case-control study." in: J Epidemiol, Vol. 7, Issue 3, pp. 143-51, 1997 (PubMed).

Yoshihara, Sumii, Haruma et al.: "The usefulness of gastric mass screening using serum pepsinogen levels compared with photofluorography." in: Hiroshima journal of medical sciences, Vol. 46, Issue 2, pp. 81-6, 1997 (PubMed).

Hattori, Tashiro, Kawamoto et al.: "Sensitivity and specificity of mass screening for gastric cancer using the measurment of serum pepsinogens." in: Japanese journal of cancer research : Gann, Vol. 86, Issue 12, pp. 1210-5, 1996 (PubMed).

Kikuchi S, Wada O, Miki K et al.: "Serum pepsinogen as a new marker for gastric carcinoma among young adults. Research Group on Prevention of Gastric Carcinoma among Young Adults." in: Cancer, Vol. 73, Issue 11, pp. 2695-702, 1994 (PubMed).

Sipponen, Kekki, Haapakoski et al.: "Gastric cancer risk in chronic atrophic gastritis: statistical calculations of cross-sectional data." in: International journal of cancer. Journal international du cancer, Vol. 35, Issue 2, pp. 173-7, 1985 (PubMed).

Farinati F, Di Mario F, Plebani M et al.: "Pepsinogen A/pepsinogen C or pepsinogen A multiplied by gastrin in the diagnosis of gastric cancer?" in: Ital J Gastroenterol, Vol. 23, Issue 4, pp. 194-6, 1991 (PubMed).

Varis, Samloff, Ihämaki et al.: "An appraisal of tests for severe atrophic gastritis in relatives of patients with pernicious anemia." in: Digestive diseases and sciences, Vol. 24, Issue 3, pp. 187-91, 1979 (PubMed).