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Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody

Details for Product No. ABIN108610, Supplier: Log in to see
Antigen
  • D15Ertd119e
  • Hdp
  • hnrnp-A1
  • hnRNP-A1
  • hnRNP A1
  • HNRNPA1
  • HNRPA1
  • Hnrpa1
  • hnrpa1
  • HNRPA1L3
  • ROA1
  • TPT1P
Reactivity
Mouse (Murine), Human
114
52
34
21
19
4
3
3
1
Host
Mouse
89
26
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
5
5
5
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
103
65
42
39
24
23
14
13
1
1
1
Supplier
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Immunogen Full length hnRNP-A1 native protein (partially purified) from HeLa cells (human)
Clone 9H10
Isotype IgG2b
Purification Protein A
Alternative Name hnRNP A1 (HNRNPA1 Antibody Abstract)
Background Synonyms:
HNRNPA 1 antibody,Helix destabilizing protein antibody,Helix-destabilizing proteinantibody,Heterogeneous nuclear ribonucleoprotein A1 antibody,Heterogeneous nuclear ribonucleoprotein A1B proteinantibody,Heterogeneous nuclear ribonucleoprotein B2 protein antibody,Heterogeneous nuclear ribonucleoprotein coreprotein A1 antibody,hnRNP A1 antibody,hnRNP core protein A1 antibody,HNRNPA1 antibody,HNRPA1antibody,MGC102835 antibody,Nuclear ribonucleoprotein particle A1 protein antibody,ROA1_HUMANantibody
Gene ID 3178, 15382
OMIM 164017
UniProt P49312
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, Flow Cyt: Use 1 μg for 106 cells. IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval before commencing with IHC staining protocol WB: Use at 1:2000-1:4000. Detects a band of approximately 34 kDa (predicted molecular weight: 38 kDa) IP: Use at an assay dependent dilution. This antibody does not IP the hnRNP complex
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN108610) Western blot for anti-hnRNP-A1 on HeLa cell extracts
 image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN108610) anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (Image 2)
 image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN108610) anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (Image 3)
Product cited in: Woolley, Algie, Samuel, Harfoot, Wiles, Hung, Tan, Hains, Valova, Huschtscha, Royds, Perez, Yoon, Cohen, Robinson, Bay, Lasham, Braithwaite: "Prognostic association of YB-1 expression in breast cancers: a matter of antibody." in: PLoS ONE, Vol. 6, Issue 6, pp. e20603, 2011 (PubMed).

Beauchamp, Nassif, Hillock, van der Giessen, von Roretz, Jasmin, Gallouzi: "The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation." in: Cell death and differentiation, Vol. 17, Issue 10, pp. 1588-99, 2010 (PubMed).

Read, Digard: "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1290-301, 2010 (PubMed).

Rosenberger, De-Castro Arce, Langbein, Steenbergen, Rösl: "Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 7006-11, 2010 (PubMed).

Sellier, Rau, Liu, Tassone, Hukema, Gattoni, Schneider, Richard, Willemsen, Elliott, Hagerman, Charlet-Berguerand: "Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients." in: The EMBO journal, Vol. 29, Issue 7, pp. 1248-61, 2010 (PubMed).

Kocgozlu, Lavalle, Koenig, Senger, Haikel, Schaaf, Voegel, Tenenbaum, Vautier: "Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells." in: Journal of cell science, Vol. 123, Issue Pt 1, pp. 29-39, 2009 (PubMed).

Lieberthal, Kaminsky, Parkhurst, Tanese: "The role of YY1 in reduced HP1alpha gene expression in invasive human breast cancer cells." in: Breast cancer research : BCR, Vol. 11, Issue 3, pp. R42, 2009 (PubMed).

Kashima, Rao, David, Manley: "hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing." in: Human molecular genetics, Vol. 16, Issue 24, pp. 3149-59, 2007 (PubMed).

van der Giessen, Gallouzi: "Involvement of transportin 2-mediated HuR import in muscle cell differentiation." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2619-29, 2007 (PubMed).

Matunis, Xing, Dreyfuss: "The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization." in: Nucleic acids research, Vol. 22, Issue 6, pp. 1059-67, 1994 (PubMed).