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Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody

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Synonyms hnrpa1, TPT1P, HNRPA1, HNRNPA1, hnRNP A1, HNRPA1L3, hnRNP-A1, D15Ertd119e, Hdp, Hnrpa1, hnrnp-A1, ROA1
Mouse (Murine), Human
(96), (31), (29), (7), (5), (4), (3), (3), (1)
(85), (13)
Clonality (Clone)
Monoclonal ()
(5), (5), (5), (2), (2), (2)
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
(85), (52), (32), (25), (10), (10), (8), (1), (1), (1)
Pubmed 10 references available
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Quantity 50 μL
Shipping to United States ( )
Availability Will be delivered in 5 to 6 Business Days
Immunogen Full length hnRNP-A1 native protein (partially purified) from HeLa cells (human)
Clone 9H10
Isotype IgG2b
Characteristics Myeloma fusion partners:
Balb/c Sp2/0 cell line
Detects a band of approximately 34 kDa (predicted molecular weight: 38 kDa)
Purification Protein A
Alternative Name hnRNP A1 (HNRNPA1 Antibody Abstract)
Background Synonyms:
HNRNPA 1 antibody,Helix destabilizing protein antibody,Helix-destabilizing proteinantibody,Heterogeneous nuclear ribonucleoprotein A1 antibody,Heterogeneous nuclear ribonucleoprotein A1B proteinantibody,Heterogeneous nuclear ribonucleoprotein B2 protein antibody,Heterogeneous nuclear ribonucleoprotein coreprotein A1 antibody,hnRNP A1 antibody,hnRNP core protein A1 antibody,HNRNPA1 antibody,HNRPA1antibody,MGC102835 antibody,Nuclear ribonucleoprotein particle A1 protein antibody,ROA1_HUMANantibody
UniProt P49312
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, Flow Cyt: Use 1µg for 106 cells. IHC-P: Use a concentration of 1 µg/mL. Perform heat mediated antigen retrieval before commencing with IHC staining protocol WB: Use at 1:2000-1:4000. IP: Use at an assay dependent dilution. This antibody does not IP the hnRNP complex
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 0.1 % sodium azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN108610) Western blot for anti-hnRNP-A1 on HeLa cell extracts
 image for anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (ABIN108610) anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody (Image 2)
Product cited in: Woolley, Algie, Samuel et al.: "Prognostic association of YB-1 expression in breast cancers: a matter of antibody." in: PLoS ONE, Vol. 6, Issue 6, pp. e20603, 2011 (PubMed).

Beauchamp, Nassif, Hillock et al.: "The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation." in: Cell death and differentiation, Vol. 17, Issue 10, pp. 1588-99, 2010 (PubMed).

Rosenberger, De-Castro Arce, Langbein et al.: "Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 7006-11, 2010 (PubMed).

Sellier, Rau, Liu et al.: "Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients." in: The EMBO journal, Vol. 29, Issue 7, pp. 1248-61, 2010 (PubMed).

Read, Digard: "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1290-301, 2010 (PubMed).

Kocgozlu, Lavalle, Koenig et al.: "Selective and uncoupled role of substrate elasticity in the regulation of replication and transcription in epithelial cells." in: Journal of cell science, Vol. 123, Issue Pt 1, pp. 29-39, 2009 (PubMed).

Lieberthal, Kaminsky, Parkhurst et al.: "The role of YY1 in reduced HP1alpha gene expression in invasive human breast cancer cells." in: Breast cancer research : BCR, Vol. 11, Issue 3, pp. R42, 2009 (PubMed).

Kashima, Rao, David et al.: "hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing." in: Human molecular genetics, Vol. 16, Issue 24, pp. 3149-59, 2007 (PubMed).

van der Giessen, Gallouzi: "Involvement of transportin 2-mediated HuR import in muscle cell differentiation." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2619-29, 2007 (PubMed).

Matunis, Xing, Dreyfuss: "The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization." in: Nucleic acids research, Vol. 22, Issue 6, pp. 1059-67, 1994 (PubMed).

Catalog No. ABIN108610
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