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Forkhead Box P1 (FOXP1) (AA 481-677) antibody

Details for Product No. ABIN1098120
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Antigen
Synonyms foxp1, im:7139058, wu:fc83a06, FOXP1, MGC145686, 12CC4, QRF1, hFKH1B, 3110052D19Rik, 4932443N09Rik, AI461938, AW494214
Epitope
AA 481-677
(27), (7), (5), (3), (3), (2), (2), (1), (1)
Reactivity
Human
(75), (28), (22), (14), (14), (14)
Host
Mouse
(58), (18)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
(54), (28), (20), (20), (16), (10), (7), (4), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN1098120
396.00 $
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Immunogen Purified recombinant fragment of human FOXP1 (AA 481-677) expressed in E. coli.
Clone 6-00E-04
Isotype IgG1
Purification Purified
Alternative Name FOXP1
Background Synonyms:
QRF1, 12CC4, hFKH1B, HSPC215, FLJ23741, MGC12942, MGC88572, MGC99551
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14. 1) reported to contain a tumor suppressor gene (s). Alternative splicing results in multiple transcript variants encoding different isoforms.
Molecular Weight 75.3 kDa
Gene ID 27086
Research Area Cancer, Transcription Factors
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng)
anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody (2) Figure 3: Flow cytometric analysis of Jurkat cells using FOXP1 mouse mAb (green) and negative control (red) .
anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody (3) Figure 4: Immunohistochemical analysis of paraffin-embedded breast cancer tissues using FOXP1 mouse mAb with DAB staining.
anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody (4) Figure 5: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using FOXP1 mouse mAb with DAB staining.
anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody (5) Figure 2: Western blot analysis using FOXP1 mouse mAb against HeLa (1), Jurkat (2), MCF-7 (3), T47D (4), and Raw264.7 (5) cell lysate.
anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody (6) Figure 1: Western blot analysis using FOXP1 mAb against human FOXP1 recombinant protein. (Expected MW is 47.7 kDa)
Product cited in: Jones, Bhattacharyya, Simkus et al.: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, 2011 (PubMed).

Chen, Xiao, Zhang et al.: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, 2011 (PubMed).

Validation Images
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