Recombination Activating Gene 1 (RAG1) (AA 818-868) antibody

Details for Product No. ABIN1098121
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Antigen
Synonyms RAG-1, rag1, RNF74, Rag-1, rag-1, rag1a
Epitope
AA 818-868
(6), (4), (1), (1)
Reactivity
Human
(18), (15), (11), (6), (3)
Host
Mouse
(25), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(10), (9), (9), (2)
Pubmed 2 references available
Quantity 0.1 mg
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Immunogen Purified recombinant fragment of human RAG1 (AA 818-868) expressed in E. coli.
Clone 1D9
Isotype IgG1
Purification Purified
Alternative Name RAG1 (RAG1 Antibody Abstract)
Background Synonyms:
RAG-1, RNF74, MGC43321
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
Molecular Weight 119 kDa
Gene ID 5896
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Recombination Activating Gene 1 (RAG1) (AA 818-868) antibody Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: ...
anti-Recombination Activating Gene 1 (RAG1) (AA 818-868) antibody (2) Figure 1: Western blot analysis using RAG1 mAb against human RAG1 recombinant protein...
anti-Recombination Activating Gene 1 (RAG1) (AA 818-868) antibody (3) Figure 2: Western blot analysis using RAG1 mAb against HEK293 (1) and RAG1 (AA: 818-8...
Product cited in: Chen, Xiao, Zhang et al.: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, 2011 (PubMed).

Jones, Bhattacharyya, Simkus et al.: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, 2011 (PubMed).

Validation Images
Catalog No. ABIN1098121
430.10 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
430.10 $

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