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alpha Tubulin / TUBA1A / TUBA3 antibody

Details for Product No. ABIN1105303, Supplier: Log in to see
Antigen
Reactivity
Human, Rat (Rattus)
1
1
1
Host
Mouse
1
Clonality (Clone)
Monoclonal ()
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
1
1
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Immunogen Microtubules from chicken embryo brain
Clone Tub-1
Isotype IgG1
Specificity This antibody reacts to TUBA1A / TUBA3.
Purification Affinity chromatography
Background Alpha-tubulin (b-alpha-1) mRNA is expressed only in brain with a molecular weight of about 55,000. The 3-prime UTR of b-alpha-1 is more than 80 % homologous to the UTR of the rat brain alpha-tubulin gene,IL-alpha-T1. B-alpha-1 encodes a predicted 451-amino acid protein that is 100 % identical to the rat homolog and differs by only 2 and 3 amino acids from the pig and chicken homologs, respectively.Synonyms: Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-1A chain, Tubulin alpha-3 chain
Gene ID 7846
NCBI Accession NP_006000
UniProt Q71U36
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (IHC) image for anti-alpha Tubulin / TUBA1A / TUBA3 antibody (ABIN1105303) anti-alpha Tubulin / TUBA1A / TUBA3 antibody
Background publications Cowan, Dobner, Fuchs et al.: "Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions." in: Molecular and cellular biology, Vol. 3, Issue 10, pp. 1738-45, 1984 (PubMed).

Hall, Cowan: "Structural features and restricted expression of a human alpha-tubulin gene." in: Nucleic acids research, Vol. 13, Issue 1, pp. 207-23, 1985 (PubMed).