Actinin, alpha 1 (ACTN1) antibody

Details for Product No. ABIN1105322
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Synonyms ACTN1, actinin, BDPLT15, 3110023F10Rik, Actn1a
Human, Mouse (Murine), Rabbit, Rat (Rattus)
(68), (20), (17), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
(54), (17), (2)
Clonality (Clone)
Monoclonal ()
(2), (2), (2), (2), (2), (2)
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(69), (32), (29), (17), (11), (6), (6), (5), (4), (3), (2), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Rabbit skeletal alpha-actinin
Clone SA-20
Isotype IgG1
Specificity This antibody reacts to Alpha-actinin-1.
Purification Affinity chromatography
Alternative Name alpha-Actinin-1 / ACTN1 (ACTN1 Antibody Abstract)
Background Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.Synonyms: Alpha actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin 1
Gene ID 87
NCBI Accession NP_001093
UniProt P12814
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Youssoufian, McAfee, Kwiatkowski: "Cloning and chromosomal localization of the human cytoskeletal alpha-actinin gene reveals linkage to the beta-spectrin gene." in: American journal of human genetics, Vol. 47, Issue 1, pp. 62-72, 1990 (PubMed).

Catalog No. ABIN1105322
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