You are viewing an incomplete version of our website. Please click to reload the website as full version.

Actinin, alpha 1 (ACTN1) antibody

Details for Product No. ABIN1105322, Supplier: Login to see
Antigen
  • ACTN1
  • actinin
  • BDPLT15
  • 3110023F10Rik
  • Actn1a
Reactivity
Human, Mouse (Murine), Rabbit, Rat (Rattus)
69
23
20
7
4
2
2
2
1
1
1
1
1
1
1
Host
Mouse
58
16
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
69
32
31
17
9
5
5
5
4
2
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Immunogen Rabbit skeletal alpha-actinin
Clone SA-20
Isotype IgG1
Specificity This antibody reacts to Alpha-actinin-1.
Purification Affinity chromatography
Alternative Name alpha-Actinin-1 / ACTN1 (ACTN1 Antibody Abstract)
Background Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.Synonyms: Alpha actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin 1
Gene ID 87
NCBI Accession NP_001093
UniProt P12814
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Youssoufian, McAfee, Kwiatkowski: "Cloning and chromosomal localization of the human cytoskeletal alpha-actinin gene reveals linkage to the beta-spectrin gene." in: American journal of human genetics, Vol. 47, Issue 1, pp. 62-72, 1990 (PubMed).