Caldesmon 1 (CALD1) antibody

Details for Product No. ABIN1105638
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Antigen
Synonyms CALD1, caldesmon, si:bz30i22.4, si:rp71-30i22.4, zgc:56389, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22, 4833423D12Rik, AI195384, AV071549, AW536160, C920027I18Rik, l-Cad
Reactivity
Human
(143), (74), (69), (26), (25), (17), (4), (4), (2), (2), (1), (1), (1), (1)
Host
Mouse
(117), (36)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(117), (57), (42), (40), (34), (20), (16), (13), (8), (4), (4), (4), (3), (2), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN1105638
308.00 $
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Immunogen Caldesmon from turkey gizzard
Clone CD-7
Isotype IgG1
Specificity This antibody reacts to Caldesmon (smooth).
Purification Affinity chromatography
Alternative Name Caldesmon
Background Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells.The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons.Synonyms: CAD, CALD1, CDM
Gene ID 800
NCBI Accession NP_004333
UniProt Q05682
Research Area Cardiovascular, Contractility, Cytoskeleton, Microfilaments
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Humphrey, Herrera-Sosa, Gonzalez et al.: "Cloning of cDNAs encoding human caldesmons." in: Gene, Vol. 112, Issue 2, pp. 197-204, 1992 (PubMed).

Hayashi, Yano, Hashida et al.: "Genomic structure of the human caldesmon gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 24, pp. 12122-6, 1993 (PubMed).

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