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Caldesmon antibody (Caldesmon 1)

Details for Product anti-CALD1 Antibody No. ABIN1105638, Supplier: Login to see
Antigen
  • CALD1
  • caldesmon
  • si:bz30i22.4
  • si:rp71-30i22.4
  • zgc:56389
  • CDM
  • H-CAD
  • HCAD
  • L-CAD
  • LCAD
  • NAG22
  • 4833423D12Rik
  • AI195384
  • AV071549
  • AW536160
  • C920027I18Rik
  • l-Cad
Reactivity
Human
160
75
68
6
5
3
3
2
1
1
1
1
1
1
Host
Mouse
129
42
Clonality (Clone)
Monoclonal ()
Conjugate
This Caldesmon antibody is un-conjugated
4
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
120
55
46
44
37
22
19
15
11
5
4
3
1
1
Supplier
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Immunogen Caldesmon from turkey gizzard
Clone CD-7
Isotype IgG1
Specificity This antibody reacts to Caldesmon (smooth).
Purification Affinity chromatography
Alternative Name Caldesmon (CALD1 Antibody Abstract)
Background Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells.The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons.Synonyms: CAD, CALD1, CDM
Gene ID 800
NCBI Accession NP_004333
UniProt Q05682
Research Area Cardiovascular, Contractility, Cytoskeleton, Microfilaments
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Humphrey, Herrera-Sosa, Gonzalez et al.: "Cloning of cDNAs encoding human caldesmons." in: Gene, Vol. 112, Issue 2, pp. 197-204, 1992 (PubMed).

Hayashi, Yano, Hashida et al.: "Genomic structure of the human caldesmon gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 24, pp. 12122-6, 1993 (PubMed).