CD48 Molecule (CD48) antibody (APC)

Details for Product No. ABIN1106423
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AI449234, AW610730, BCM1, BLAST, BLAST-1, BLAST1, Bcm-1, MEM-102, SLAMF2, Sgp-60, hCD48, mCD48
Reactivity
Human, Monkey
(108), (91), (43), (12), (12), (5), (3), (2), (1)
Host
Mouse
(98), (58), (33), (26), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
APC
(34), (25), (16), (11), (8), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(154), (54), (39), (24), (19), (10), (8), (5), (5), (4), (3), (3)
Pubmed 4 references available
Quantity 100 tests
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1106423
753.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Clone MEM-102
Isotype IgG1
Specificity This antibody recognises the CD48 antigen which is widely distributed on leucocytes with a distinctive reaction pattern. The antigen is structurally closely related to the B-cell activation antigen Blast-1.
Purification Purified IgG prepared by ion exchange chromatography.
Alternative Name CD48
Background CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.
Alternate names: B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, Leukocyte antigen MEM-102, MEM-102, TCT.1
Gene ID 962
NCBI Accession NP_001769
UniProt P09326
Research Area CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute with 1 mL distilled water.
Concentration 0.1 mg/mL
Buffer PBS containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Prior to and following reconstitution store the antibody at 2-8°C.
Expiry Date 12 months
Background publications Cinek, Horejsí: "The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 7, pp. 2262-70, 1992 (PubMed).

Korínek, Stefanová, Angelisová et al.: "The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1." in: Immunogenetics, Vol. 33, Issue 2, pp. 108-12, 1991 (PubMed).

Horejsí, Angelisová, Bazil et al.: "Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74)." in: Folia biologica, Vol. 34, Issue 1, pp. 23-34, 1988 (PubMed).

Staffler, Szekeres, Schütz et al.: "Selective inhibition of T cell activation via CD147 through novel modulation of lipid rafts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 4, pp. 1707-14, 2003 (PubMed).

Validation Images
Did you look for something else?
back to top