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Gastrin antibody (GAST)

Details for Product anti-GAST Antibody No. ABIN115354, Supplier: Login to see New
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Synonyms GAST, GAS, Gas, PPG34, C16orf53, PA1
(111), (35), (34), (5), (3), (2), (2), (2), (2), (2), (1), (1), (1)
(116), (9), (4)
This Gastrin antibody is un-conjugated
(7), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(54), (43), (36), (32), (22), (19), (15), (11), (8), (6), (4), (3), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant Gastrin conjugated to KLH.
Specificity The antibody is specific against gastrin-containing cells. This antibody reacts with human gastrin I and human gastrin I fragments.
Cellular Localization: Cytoplasmic
Purification Purified
Alternative Name Gastrin (GAST Antibody Abstract)
Background Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.Synonyms: GAS, GAST
Gene ID 2520
NCBI Accession NP_000796
UniProt P01350
Research Area Cardiovascular, Atherosclerosis, Hormones
Application Notes Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Stomach
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer containing sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Degli-Esposti, Smolak, Walczak et al.: "Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family." in: The Journal of experimental medicine, Vol. 186, Issue 7, pp. 1165-70, 1997 (PubMed).

Pan, Ni, Wei et al.: "An antagonist decoy receptor and a death domain-containing receptor for TRAIL." in: Science (New York, N.Y.), Vol. 277, Issue 5327, pp. 815-8, 1997 (PubMed).

Catalog No. ABIN115354
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