Gastrin (GAST) antibody
| Antigen |
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| Synonyms |
GAS, Gas, PPG34, GAST, CCKBR, CCK-B, CCK-BR, CCK2-R |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Conjugate
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FITC (3), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE (2), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
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Application
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Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Immunofluorescence (IF) (39), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (29), Western Blotting (WB) (19), ELISA (18), Immunohistochemistry (IHC) (10), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (8), Radioimmunoassay (RIA) (7), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunocytochemistry (ICC) (3), Immunoprecipitation (IP) (3), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Dot Blot (Dot) (1)
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| Catalog no. |
ABIN115354 |
| Quantity |
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| Price |
363.00 $ Plus shipping costs $45.00
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| Shipping to |
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| Availability |
Will be delivered in 6 to 8 Business Days |
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Alternative name
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Gastrin
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UniProt
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P01350
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Immunogen
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Recombinant Gastrin conjugated to KLH.
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Cross-Reactivity
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Human
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Description
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Gastrin is mainly known by its first described role as a gastric acid-hormone but the proteinalso has the ability to promote cellular growth. More recently, gastrin has been suggestedto induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate twodifferent receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinityfor the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has highaffinity for both gastrin and CCK and mediates the acid-secretory as well as theproliferative effects of gastrin.
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Characteristics
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Synonyms: GAST, GAS
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Application Notes
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Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: StomachOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Purified
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Buffer
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containing sodium azide as preservative
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Cardiovascular, Atherosclerosis, Hormones
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Restrictions
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For Research Use only
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Pan, Ni, Wei et al.: "An antagonist decoy receptor and a death domain-containing receptor for TRAIL." in: Science (New York, N.Y.), Vol. 277, Issue 5327, pp. 815-8, 1997 (PubMed).
Degli-Esposti, Smolak, Walczak et al.: "Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family." in: The Journal of experimental medicine, Vol. 186, Issue 7, pp. 1165-70, 1997 (PubMed).
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Alternatives for antigen "Gastrin (GAST)", type "Antibodies"
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Hosts
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Rabbit (82), Guinea Pig (2), Mouse (2)
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Reactivities
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Human (74), Mouse (Murine) (39), Rat (Rattus) (39), Pig (Porcine) (18)
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Applications
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Immunofluorescence (IF) (39), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (29), Western Blotting (WB) (19), ELISA (18), Immunohistochemistry (IHC) (10), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (8), Radioimmunoassay (RIA) (7), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunocytochemistry (ICC) (3), Immunoprecipitation (IP) (3), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Dot Blot (Dot) (1)
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Conjugates
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FITC (3), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE (2), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
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Epitopes
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Internal Region (3), N-Term (2), AA 1-34 (1), AA 17 (1), C-Term (1)
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