Gastrin antibody
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- Target See all Gastrin (GAST) Antibodies
- Gastrin (GAST)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Gastrin antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
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The antibody is specific against gastrin-containing cells. This antibody reacts with human gastrin I and human gastrin I fragments.
Cellular Localization: Cytoplasmic - Purification
- Purified
- Immunogen
- Recombinant Gastrin conjugated to KLH.
- Top Product
- Discover our top product GAST Primary Antibody
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- Application Notes
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Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 100 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Stomach
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- containing sodium azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Gastrin (GAST)
- Alternative Name
- Gastrin (GAST Products)
- Synonyms
- GAS antibody, Gas antibody, PPG34 antibody, GAST antibody, gastrin antibody, GAST antibody, Gast antibody
- Background
- Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin.Synonyms: GAS, GAST
- Gene ID
- 2520
- NCBI Accession
- NP_000796
- UniProt
- P01350
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