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CEBPB antibody (CCAAT/enhancer Binding Protein (C/EBP), beta) (AA 1-271)

Details for Product anti-CEBPB Antibody No. ABIN121153, Supplier: Login to see
Antigen
  • C/EBPbeta
  • c/ebp-beta
  • crp2
  • il6dbp
  • lap
  • nf-il6
  • tcf5
  • xC/EBPbeta
  • cebpbb
  • cb380
  • c/ebpb
  • fe11e05
  • wu:fe11e05
  • CEBPB
  • LOC100136165
  • C/EBP-beta
  • CRP2
  • IL6DBP
  • LAP
  • NF-IL6
  • TCF5
  • IL-6DBP
  • LIP
  • NF-M
  • Nfil6
  • Il6dbp
Alternatives
anti-Human CEBPB antibody for Immunoprecipitation
Epitope
AA 1-271, N-Term
14
12
9
8
6
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
95
59
43
10
8
3
Host
Mouse
81
34
10
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CEBPB antibody is un-conjugated
5
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
101
51
28
18
14
13
10
10
5
3
3
2
2
2
1
1
Supplier
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Immunogen Recombinant human C/EBP-beta (1-271 aa) purified from E. coli
Clone 47A1
Isotype IgG1
Purification Protein-G affinity chromatography
Alternative Name CEBPB (CEBPB Antibody Abstract)
Background CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPα, C/EBPβ, C/EBPδ, C/EBPε, and C/EBPγ. Among these proteins, C/EBPβ is usually highly expressed in liver, intestine, lung and adipose. C/EBPβ has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated.Synonyms: C/EBP beta, CCAAT/enhancer-binding protein beta, LAP, Liver activator protein, NF-IL6, Nuclear factor NF-IL6, TCF5, Transcription factor 5
UniProt P17676
Pathways Interferon-gamma Pathway
Application Notes ELISA. Western blot (1/500 - 1/2,000), recommended starting dilution is 1:1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-CEBPB antibody (CCAAT/enhancer Binding Protein (C/EBP), beta) (AA 1-271) (ABIN121153) Western blot analysis.,.NIH 3T3 cell lysates were resolved by SDS-PAGE, transferred t...
Background publications Su, Chou, Chang et al.: "Differential activation of a C/EBP beta isoform by a novel redox switch may confer the lipopolysaccharide-inducible expression of interleukin-6 gene." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 51150-8, 2003 (PubMed).

Parkin, Baer, Copeland et al.: "Regulation of CCAAT/enhancer-binding protein (C/EBP) activator proteins by heterodimerization with C/EBPgamma (Ig/EBP)." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23563-72, 2002 (PubMed).

Lekstrom-Himes, Xanthopoulos: "Biological role of the CCAAT/enhancer-binding protein family of transcription factors." in: The Journal of biological chemistry, Vol. 273, Issue 44, pp. 28545-8, 1998 (PubMed).