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Details for Product No. ABIN121153

CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 1-271), (N-Term) antibody

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Antigen
Synonyms
C/EBP-beta, CRP2, IL6DBP, LAP, NF-IL6, TCF5, C/EBPbeta, IL-6DBP, LIP, NF-M, Nfil6, Il6dbp, c/ebp-beta, crp2, il6dbp, lap, nf-il6, tcf5, xC/EBPbeta, cebpbb, cb380, c/ebpb, fe11e05, wu:fe11e05, CEBPB, L ... show more
Epitope
»Alternatives AA 1-271, N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Pubmed 3 references available
Catalog no. ABIN121153
Quantity 0.1 mL
Price
401.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant human C/EBP-beta (1-271 aa) purified from E. coli
Clone 47A1
Isotype IgG1
Purification Protein-G affinity chromatography
Alternative Name CEBPB
Background CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBP a , C/EBP b , C/EBP d , C/EBP e , and C/EBP g . Among these proteins, C/EBP b is usually highly expressed in liver, intestine, lung and adipose. C/EBP b has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated. Alternate Names: C/EBP beta, NF-IL6, TCF5, CCAAT/enhancer-binding protein beta, Nuclear factor NF-IL6, Transcription factor 5.
UniProt P17676
Application Notes ELISA. Western blot (1/500 - 1/2,000), recommended starting dilution is 1:1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Lekstrom-Himes, Xanthopoulos: "Biological role of the CCAAT/enhancer-binding protein family of transcription factors." in: The Journal of biological chemistry, Vol. 273, Issue 44, pp. 28545-8, 1998 (PubMed).

Parkin, Baer, Copeland et al.: "Regulation of CCAAT/enhancer-binding protein (C/EBP) activator proteins by heterodimerization with C/EBPgamma (Ig/EBP)." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23563-72, 2002 (PubMed).

Su, Chou, Chang et al.: "Differential activation of a C/EBP beta isoform by a novel redox switch may confer the lipopolysaccharide-inducible expression of interleukin-6 gene." in: The Journal of biological chemistry, Vol. 278, Issue 51, pp. 51150-8, 2003 (PubMed).

Alternatives for antigen "CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB)", type "Antibodies"
Hosts (76), (31), (2)
Reactivities (91), (71), (56), (27), (26), (12), (12), (1), (1), (1), (1), (1), (1)
Applications (80), (46), (30), (21), (15), (13), (9), (7), (5), (1), (1), (1), (1), (1)
Conjugates (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (17), (13), (9), (6), (5), (5), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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