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Details for Product No. ABIN121161

Adiponectin, C1Q and Collagen Domain Containing (ADIPOQ) (AA 15-244) antibody

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Antigen
Synonyms ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28, APN, Acdc, apM1, 30kDa, adipo, Acrp30, ADN, MGC84292, ADIPOQ
Epitope
»Alternatives AA 15-244
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN121161
Quantity 0.1 mL
Price
401.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant human adiponectin (15-244 aa) purified from E. coli
Clone 5H7
Isotype IgG1
Purification Protein-G affinity chromatography
Alternative Name Adiponectin
Background Human Adiponectin, also referred to as AdipoQ, Acrp30, apm-1 or GBP28, is a secreted protein expressed exclusively in differentiated adipocyte (an adipokine family member). Adiponectin contains a modular structure comprising an N-terminal collagenous domain followed by a C- terminal globular domain (gAcrp30). Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Plasma levels of adiponectin are reduced in obese humans, and decreased levels are associated with insulin resistance and hyperinsulinemia. Alternate Names: ACRP30, ADIPOQ, ACDC, APM1, APM-1, GBP28, Adipocyte, C1q and collagen domain-containing protein, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, Gelatin-binding protein.
UniProt Q15848
Research Area Cancer, Atherosclerosis, Metabolism, Hormones
Application Notes ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution is 1:1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09% sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Maeda, Okubo, Shimomura et al.: "cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1)." in: Biochemical and biophysical research communications, Vol. 221, Issue 2, pp. 286-9, 1996 (PubMed).

Berg, Combs, Du et al.: "The adipocyte-secreted protein Acrp30 enhances hepatic insulin action." in: Nature medicine, Vol. 7, Issue 8, pp. 947-53, 2001 (PubMed).

Berg, Combs, Scherer: "ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism." in: Trends in endocrinology and metabolism: TEM, Vol. 13, Issue 2, pp. 84-9, 2002 (PubMed).

Yamauchi, Kamon, Minokoshi et al.: "Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase." in: Nature medicine, Vol. 8, Issue 11, pp. 1288-95, 2002 (PubMed).

Alternatives for antigen "Adiponectin, C1Q and Collagen Domain Containing (ADIPOQ)", type "Antibodies"
Hosts (196), (140), (12), (7), (4), (1)
Reactivities (301), (101), (73), (16), (14), (14), (13), (2)
Applications (259), (218), (47), (37), (26), (23), (21), (11), (10), (7), (5), (4), (4), (4), (4), (3), (3), (1), (1), (1), (1)
Conjugates (31), (9), (5), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (16), (7), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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