CD16 Molecule (CD16) antibody

Details for Product No. ABIN135754
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Antigen
Synonyms Fcgr3, Fcgr3a, CD16, FCGR3, FCGR3@, CD16b, FCG3, FCR-10, FCRIII, FCRIIIb, FcRIII
Reactivity
Human
(212), (44), (13), (4), (3), (1)
Host
Mouse
(221), (43), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(39), (32), (29), (7), (6), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)
(222), (53), (31), (30), (20), (18), (17), (16), (16), (5), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
Options
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Request Want additional data for this product?

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Catalog No. ABIN135754
140.80 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Clone GRM1
Isotype IgG2a
Characteristics The antibody detects: Human CD16/FcRIII
Purification Purified
Alternative Name CD16
Background CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Application Notes Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Sample Volume 1 mL
Restrictions For Research Use only
Buffer Product is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of phosphate buffered saline containing 0.1 % PBS / NaN3 and a stabilizing agent.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Product cited in: Mesquita, Fintelman-Rodrigues, Sacramento et al.: "HIV-1 and Its gp120 Inhibits the Influenza A(H1N1)pdm09 Life Cycle in an IFITM3-Dependent Fashion." in: PLoS ONE, Vol. 9, Issue 6, pp. e101056, 2014 (PubMed).

General Takai, Li, Sylvestre et al.: "FcR gamma chain deletion results in pleiotrophic effector cell defects." in: Cell, Vol. 76, Issue 3, pp. 519-29, 1994 (PubMed).

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