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Details for Product No. ABIN182440

General Transcription Factor III (GTF2I) (N-Term) antibody

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Antigen
Synonyms Spin, TFII-I, WBSCR6, BAP-135, GtfII-I, 6030441I21Rik, GTFII-I, BAP135, BTKAP1, DIWS, IB291, SPIN, WBS, Gtf2ird1, bap-135, bap135, btkap1, diws, gtfii-i, ib291, spin, tfii-i, wbs, wbscr6
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Dog (Canine), Rat (Rattus), Cow (Bovine), Human, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN182440
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-GTF2I antibody: synthetic peptide directed towards the N terminal of human GTF2I
Sequence ILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPD YYQYNIQGSH
Predicted Reactivity Bovine : 100%, Dog : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rat : 100%, Chicken : 92%
Characteristics This is a rabbit polyclonal antibody against GTF2I. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Affinity Purified
Alternative Name GTF2I
Background GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.
Molecular Weight 110kDa
Gene ID 2969
NCBI Accession NP_127493, NM_033000
UniProt Q75M86
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-GTF2I antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Morris, Mervis, Hobart et al.: "GTF2I hemizygosity implicated in mental retardation in Williams syndrome: genotype-phenotype analysis of five families with deletions in the Williams syndrome region." in: American journal of medical genetics. Part A, Vol. 123A, Issue 1, pp. 45-59, 2003 (PubMed).

Alternatives for antigen "General Transcription Factor III (GTF2I)", type "Antibodies"
Hosts (42), (10)
Reactivities (52), (25), (20), (2), (1), (1)
Applications (38), (19), (15), (10), (10), (4), (3), (3), (3), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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