Nuclear Receptor Co-Repressor 1 (NCOR1) (N-Term) antibody

Details for Product No. ABIN182587
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Antigen
Synonyms ncor, zgc:56355, 5730405M06Rik, A230020K14Rik, N-CoR, RIP13, Rxrip13, mKIAA1047, N-CoR1, TRAC1, hN-CoR
Epitope
N-Term
(14), (7), (7), (6), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Dog (Canine), Human
(68), (33), (16), (1)
Host
Rabbit
(55), (13), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(55), (42), (37), (10), (10), (6), (3), (3), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN182587
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human NCOR1
Sequence NENYKALVRR NYGKRRGRNQ QIARPSQEEK VEEKEEDKAE KTEKKEEEKK
Predicted Reactivity Bovine : 100 %, Human : 100 %, Mouse : 100 %, Guinea pig : 90 %, Horse : 90 %
Characteristics This is a rabbit polyclonal antibody against NCOR1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name NCOR1
Background NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Molecular Weight 270 kDa
Gene ID 9611
UniProt Q60974
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 2453 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Hörlein, Näär, Heinzel et al.: "Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor." in: Nature, Vol. 377, Issue 6548, pp. 397-404, 1995 (PubMed).

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