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Short Stature Homeobox 2 (SHOX2) (Middle Region) antibody

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Middle Region
(5), (4), (4), (3), (2), (2), (2), (2), (2)
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(25), (11), (10), (4), (3), (2), (1)
(17), (11)
Western Blotting (WB)
(26), (9), (2), (2), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Immunogen Synthetic peptide directed towards the middle region of human SHOX2
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Zebrafish : 100 %
Characteristics This is a rabbit polyclonal antibody against SHOX2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name SHOX2 (SHOX2 Antibody Abstract)
Background SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients.
Molecular Weight 35 kDa
Gene ID 6474
NCBI Accession NP_006875, NM_006884
UniProt O60902
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 331 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Short Stature Homeobox 2 (SHOX2) (Middle Region) antibody (ABIN182771) anti-Short Stature Homeobox 2 (SHOX2) (Middle Region) antibody
Background publications Blaschke, Monaghan, Schiller et al.: "SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 5, pp. 2406-11, 1998 (PubMed).

Catalog No. ABIN182771

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