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Snail Homolog 1 (Drosophila) (SNAI1) (N-Term) antibody

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Antigen
Synonyms
SNAI1, BG:DS01845.1, CG3956, Dmel\\CG3956, SNA, Sco, Sna, br28, br29, l(2)35Db, l(2)br28, l(2)br29, l(3)br28, l35Db, sn, Xsnail, sna, snail1, xSna, Snai, SLUGH2, SNAH, SNAIL, SNAIL1, dJ710H13.1, AI194 ... show more
SNAI1, BG:DS01845.1, CG3956, Dmel\\CG3956, SNA, Sco, Sna, br28, br29, l(2)35Db, l(2)br28, l(2)br29, l(3)br28, l35Db, sn, Xsnail, sna, snail1, xSna, Snai, SLUGH2, SNAH, SNAIL, SNAIL1, dJ710H13.1, AI194338, Sna1, Snail, Snail1 show less
Epitope
N-Term
(43), (13), (8), (7), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(141), (41), (12), (2), (2), (2)
Host
Rabbit
(93), (27), (18), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (3), (3), (3)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(127), (67), (24), (23), (11), (11), (6), (5), (1), (1), (1), (1)
Pubmed 4 references available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human SNAI1
Blocking Peptide Blocking peptide for this product available: ABIN984164
Sequence MPRSFLVRKP SDPNRKPNYS ELQDSNPEFT FQQPYDQAHL LAAIPPPEIL
Predicted Reactivity Human : 100 %, Mouse : 90 %, Rat : 90 %
Characteristics This is a rabbit polyclonal antibody against SNAI1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name SNAI1 (SNAI1 Antibody Abstract)
Background The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo.
Molecular Weight 29 kDa
Gene ID 6615
NCBI Accession NP_005976, NM_005985
UniProt O95863
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 264 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Image no. 1 for anti-Snail Homolog 1 (Drosophila) (SNAI1) (N-Term) antibody (ABIN182776) WB Suggested Anti-SNAI1 Antibody Titration: 1ug/ml
Positive Control:
Immunohistochemistry (IHC) image for anti-Snail Homolog 1 (Drosophila) (SNAI1) (N-Term) antibody (ABIN182776) IHC Suggested Anti-SNAI1 Antibody Titration: 4-8ug/ml
Tissue: Human ...
Product cited in: Sihto, Lundin, Lundin et al.: "Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study." in: Breast cancer research : BCR, Vol. 13, Issue 5, pp. R87, 2012 (PubMed).

Surati, Robinson, Nandi et al.: "Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database. ..." in: Journal of clinical bioinformatics, Vol. 1, Issue 8, pp. 1-11, 2011 (PubMed).

Wang, Quah, Dong et al.: "PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition." in: Cancer research, Vol. 67, Issue 7, pp. 2922-6, 2007 (PubMed).

Background publications Zhou, Deng, Xia et al.: "Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition." in: Nature cell biology, Vol. 6, Issue 10, pp. 931-40, 2004 (PubMed).

Catalog No. ABIN182776
$289.00
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