SRY (Sex Determining Region Y)-Box 11 (SOX11) (N-Term) antibody

Details for Product No. ABIN182780
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Antigen
Synonyms XLS13, XLS13b, xSOX-11, xls13a, xsox11, SOX11, XLS13B, sox11, sox11b, sox13, xSox-13, 1110038H03Rik, 6230403H02Rik, AI836553, end1
Epitope
N-Term
(11), (7), (6), (3), (2), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human, Chicken
(37), (18), (18), (13), (13), (2), (1)
Host
Rabbit
(31), (4), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(27), (15), (10), (4), (1), (1), (1)
Pubmed 2 references available
Quantity 50 μg
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Catalog No. ABIN182780
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human SOX11
Sequence MVQQAESLEA ESNLPREALD TEEGEFMACS PVALDESDPD WCKTASGHIK
Predicted Reactivity Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Rabbit : 90 %, Mouse : 80 %, Rat : 80 %, Chicken : 70 %
Characteristics This is a rabbit polyclonal antibody against SOX11. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SOX11
Background This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.
Molecular Weight 47 kDa
Gene ID 6664
NCBI Accession NP_003099, NM_003108
UniProt P35716
Research Area Neurology, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 441 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-SRY (Sex Determining Region Y)-Box 11 (SOX11) (N-Term) antibody WB Suggested Anti-SOX11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
Background publications Wiebe, Nowling, Rizzino: "Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity." in: The Journal of biological chemistry, Vol. 278, Issue 20, pp. 17901-11, 2003 (PubMed).

General Branas, Elliott, Richmond et al.: "Alcohol consumption, alcohol outlets, and the risk of being assaulted with a gun." in: Alcoholism, clinical and experimental research, Vol. 33, Issue 5, pp. 906-15, 2009 (PubMed).

Validation Images
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