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Details for Product No. ABIN182863

Zinc Finger E-Box Binding Homeobox 2 (ZEB2) (N-Term) antibody

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Antigen
Synonyms HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B, Zfx1b, Zfhx1b, Zfxh1b, mKIAA0569, 9130203F04Rik, D130016B08Rik, sip1, XSip1, zfhx1b, si:dkey-52o2.2, sip1a, wu:fc92g08, sip1b, ZEB2
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Zebrafish (Danio rerio), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN182863
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Immunogen The immunogen for anti-ZFHX1B antibody: synthetic peptide directed towards the N terminal of human ZFHX1B
Sequence NVVDTGSETDEEDKLHIAEDDGIANPLDQETSPASVPNHE SSPHVSQALL
Predicted Reactivity Sumatran orangutan :100%,   Human :100%,   Mouse :92%,   Rat :92%,   African clawed frog :92%,   Bovine :85%,   Zebrafish :75%,   Green puffer :75%,  
Characteristics This is a rabbit polyclonal antibody against ZEB2. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name ZFHX1B
Background The ZFHX1B gene is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. ZFHX1B is strongly transcribed at an early stage in the developing peripheral and central nervous systems of both mice and humans, in all neuronal regions of the brains of 25-week human fetuses and adult mice, and in numerous nonneural tissues.The SMADIP1 gene (also known as SIP1) is a member of the delta-EF1 (ZEB1, MIM 189909)/Zfh1 family of 2-handed zinc finger/homeodomain proteins. SMADIP1 interacts with receptor-mediated, activated full-length SMADs (see MIM 605568) (Verschueren et al., 1999 [PubMed 10400677]).
Molecular Weight 136kDa
Gene ID 9839
NCBI Accession NP_055610, NM_014795
UniProt O60315
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-ZFHX1B antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Miyoshi, Kitajima, Sumi et al.: "Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells." in: British journal of cancer, Vol. 90, Issue 6, pp. 1265-73, 2004 (PubMed).

Verstappen, van Grunsven, Michiels et al.: "Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex." in: Human molecular genetics, Vol. 17, Issue 8, pp. 1175-83, 2008 (PubMed).

Alternatives for antigen "Zinc Finger E-Box Binding Homeobox 2 (ZEB2)", type "Antibodies"
Hosts (44), (7), (3)
Reactivities (55), (36), (34), (14), (8), (2), (2), (1)
Applications (46), (35), (16), (10), (9), (9), (4), (4), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (21), (9), (4), (4), (2), (2), (1), (1), (1), (1)
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