Kinesin Family Member 5A (KIF5A) (Middle Region) antibody

Details for Product No. ABIN182897
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Antigen
Synonyms KIF5A, kif5a, si:ch211-166e11.4, wu:fj61a10, nkhc, my050, spg10, d12s1889, MGC122802, D12S1889, MY050, NKHC, SPG10, D10Bwg0738e, Khc, Kif5, Kns, mKIAA4086
Epitope
Middle Region
(10), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Human
(40), (25), (22), (1)
Host
Rabbit
(39), (4)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(39), (28), (22), (7), (6), (5), (3), (3), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN182897
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human KIF5A
Sequence LEESYDSLSD ELAKLQAQET VHEVALKDKE PDTQDADEVK KALELQMESH
Predicted Reactivity Dog : 100 %, Human : 100 %, Rabbit : 100 %, Horse : 90 %, Mouse : 90 %, Rat : 90 %, Guinea pig : 80 %
Characteristics This is a rabbit polyclonal antibody against KIF5A. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name KIF5A
Background KIF5A is a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10.
Molecular Weight 117 kDa
Gene ID 3798
NCBI Accession NM_004984, NP_004975
UniProt Q12840
Research Area Cytoskeleton
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1032 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Kinesin Family Member 5A (KIF5A) (Middle Region) antibody anti-Kinesin Family Member 5A (KIF5A) (Middle Region) antibody
anti-Kinesin Family Member 5A (KIF5A) (Middle Region) antibody (2) WB Suggested Anti-KIF5A
Antibody Titration: 0.2-1 µg/mL
Positive Control: Human brain
Background publications Reid, Kloos, Ashley-Koch et al.: "A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10)." in: American journal of human genetics, Vol. 71, Issue 5, pp. 1189-94, 2002 (PubMed).

Validation Images
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