Gap Junction Protein, gamma 1, 45kDa (GJC1) (N-Term) antibody

Details for Product No. ABIN183373
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Antigen
Synonyms cx45, gja7, MGC52735, GJA7, GJD3, GJC1, Cx30.2, Gjc1, C130009G16Rik, Cnx45, Cx45, Gja-7, Gja7, CX45
Epitope
N-Term
(12), (8), (7), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Rat (Rattus), Mouse (Murine), Cow (Bovine), Dog (Canine), Human
(53), (30), (30), (14), (14), (1), (1), (1)
Host
Rabbit
(50), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(45), (27), (13), (10), (9), (3), (2), (1)
Pubmed 2 references available
Quantity 100 μg
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Catalog No. ABIN183373
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Immunogen Synthetic peptide directed towards the N terminal of human GJC1
Sequence IFRILVLATV GGAVFEDEQE EFVCNTLQPG CRQTCYDRAF PVSHYRFWLF
Predicted Reactivity Human :100 %,   Bovine :100 %,   Dog :100 %,   Rat :100 %,   Golden hamster :100 %,   Chinese hamster :100 %,   Mouse :100 %,  
Characteristics This is a rabbit polyclonal antibody against GJC1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name GJC1
Background CX31.9 is a member of the large family of connexins that are required for the formation of gap junctions. Six connexin monomers form a hemichannel, or connexon, on the cell surface. This connexon can interact with a connexon from a neighboring cell, thus forming a channel linking the cytoplasm of the 2 cells.
Molecular Weight 32 kDa
Gene ID 125111
NCBI Accession NM_152219, NP_689343
UniProt Q6ZUW6
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 295 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Gap Junction Protein, gamma 1, 45kDa (GJC1) (N-Term) antibody WB Suggested Anti-GJC1 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
Product cited in: Terrier-Lacombe, Guillou, Maire et al.: "Dermatofibrosarcoma protuberans, giant cell fibroblastoma, and hybrid lesions in children: clinicopathologic comparative analysis of 28 cases with molecular data--a study from the French Federation of Cancer Centers Sarcoma Group." in: The American journal of surgical pathology, Vol. 27, Issue 1, pp. 27-39, 2002 (PubMed).

Background publications Söhl, Nielsen, Eiberger et al.: "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues." in: Cell communication & adhesion, Vol. 10, Issue 1, pp. 27-36, 2003 (PubMed).

Validation Images
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