Distal-Less Homeobox 4 (DLX4) (N-Term) antibody

Details for Product No. ABIN183408
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Antigen
Synonyms DLX4, BP1, DLX7, DLX8, DLX9, Dlx-4, Dlx7
Epitope
N-Term
(9), (7), (7), (5), (4), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(66), (21), (18), (16), (12), (1), (1)
Host
Rabbit
(62), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(57), (17), (14), (13), (10), (5), (4), (4), (3), (2), (2), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN183408
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of mouse DLX4
Sequence YSHPGPATPG DSYLPRQQQL VAPSQPFHRP AEHPQELEAE SEKLALSLVP
Predicted Reactivity Mouse : 100 %, Human : 90 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against DLX4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name DLX4
Background DLX4 is a member of the family of Dlx genes that are involved in early vertebrate morphogenesis, notably of the head.Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
Molecular Weight 26 kDa
Gene ID 13394
NCBI Accession NP_031893, NM_007867
UniProt P70436
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 240 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Distal-Less Homeobox 4 (DLX4) (N-Term) antibody WB Suggested Anti-DLX4 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: NIH/3T3 cell lysate
Background publications Kelly, Jerome-Majewska, Papaioannou: "The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis." in: Human molecular genetics, Vol. 13, Issue 22, pp. 2829-40, 2004 (PubMed).

Validation Images
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