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Details for Product No. ABIN183588

BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (C-Term) antibody

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Antigen
Synonyms BACH-1, 6230421P05Rik, AI323795, zgc:112205, BACH1
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN183588
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-BACH1 antibody: synthetic peptide directed towards the C terminal of human BACH1
Sequence PPCARGNSEPGYARGQESQQMSTATSEQAGPAEQCRQSGG ISDFCQQMTD
Predicted Reactivity Human : 100%, Rabbit : 85%
Characteristics This is a rabbit polyclonal antibody against BACH1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Protein A purified
Alternative Name BACH1
Background BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.
Molecular Weight 82kDa
Gene ID 571
NCBI Accession NP_001177, NM_001186
UniProt O14867
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-BACH1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Litman, Peng, Jin et al.: "BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ." in: Cancer cell, Vol. 8, Issue 3, pp. 255-65, 2005 (PubMed).

Alternatives for antigen "BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1)", type "Antibodies"
Hosts (31), (9), (5), (1)
Reactivities (44), (8), (5), (3), (1), (1)
Applications (43), (26), (10), (6), (5), (2), (2), (1), (1)
Epitopes (7), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1)
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